Urea has both emollient and keratolytic properties (TABLE 5). Furthermore, it can be combined with anthralin to improve its clinical efficacy.31 Urea combined with bifonazole is useful in the management of scalp psoriasis.31 It is used topically in concentrations of 5 to 25 in creams or lotions and up to 40 in nail preparations. The treatment of scalp psoriasis is beset with problems of drug delivery, facial irritation, messy, time-consuming, cosmetically unacceptable applications and staining of hair. First phase involves descaling using salicylic acid or urea preparations. Corticosteroids, when combined with vitamin D analogs, minimize the irritation while the total amount of corticosteroids required is low. Combined with a corticosteroid cream under occlusion, it has been found useful for palmoplantar psoriasis. Treatment of scalp seborrheic dermatitis and psoriasis with an ointment of 40 urea and 1 bifonazole.
How Do Health-Care Professionals Diagnose a Fungal Nail Infection? Topical medicines may be useful as additional therapy in combination with oral medicines. The composition of claim 19, wherein said humectant is urea. Compounds useful in the invention include those described herein in any of their pharmaceutically acceptable forms, including isomers such as diastereomers and enantiomers, salts, esters, amides, thioesters, solvates, and polymorphs thereof, as well as racemic mixtures and pure isomers of the compounds described herein. For the treatment of psoriasis, 0.01-0.15 mg/kg/day of oral tacrolimus is administered to a patient. Ciclopirox cream (penlac) is sold as an 8 topical solution for nail fungas or loprox shampoo, containing 1 ciclopirox, indicated for the treatment of seborrheic dermatitis of the scalp. Seborrhoeic dermatitis of the scalp. Medline, BMJ clinical evidence 2015, 31-May-2015 Details Seborrhoeic dermatitis affects a variable proportion of the general population, ranging from 3 to 10.
BIFONAZOLE. P. RETINOIDS FOR TREATMENT OF PSORIASIS.
Fungal Nail Infection (onychomycosis) Causes, Symptoms, Treatment