Stukalenko, (2) first established the connection of these diseases on a 24-year old male from the patient’s history and confirmed the cure of the psoriasis after tonsillectomy. Nyfors et al, (3). Treatment of psoriasis in children: is there a role for antibiotic therapy and tonsillectomy? Pediatr Dermatol 2003;20:11-15. Treatment of psoriasis in children is very conservative and many therapies used for adults may not be appropriate for children due to possible long-term or delayed adverse effects. Although prophylactic antibiotic therapy or tonsillectomy have been recommended in children with recurrent Guttate psoriasis, there are no clinical trials about it (10). Therapeutic agents including beta-blockers, lithium, antimalaria, NSAID, withdrawal oral or topical potent steroids play an important role in development or rebound of psoriasis. The results confirmed acceptability of treatment and there was no significant reduction in psoriasis area severity index (PASI) between the two groups (20). Psoriasis was cleared completely after tonsillectomy in five out of the six patients (83 ) with guttate psoriasis and was improved in one patient. Treatment of psoriasis in children: is there a role for antibiotic therapy and tonsillectomy?.
Abstract. Long-term therapy with the macrolide antibiotic erythromycin was shown to alter the clinical course of diffuse panbronchiolitis in the late 1980s. Macrolides are widely used to treat infections of soft tissues and of the respiratory tract due to their efficacy against Gram-negative and Gram-positive bacteria, including intracellular germs such as Chlamydia and Legionella 2 4. Feldman, Treatment of psoriasis in children: is there a role for antibiotic therapy and tonsillectomy? In many cases, these children had been unsuccessfully treated for pinworms, candidal infection, perianal psoriasis, seborrheic dermatitis, or eczema. In each of these cases, the psoriatic lesions resolved with oral antistreptococcal therapy. In an uncontrolled trial and a case-controlled, prospective, unblinded study, patients with plaque psoriasis were treated with macrolide antibiotics for a 4-week course. There have been 2 larger studies exploring the role of tonsillectomy in patients with psoriasis. In laryngitis there are few visible signs of infection but with soreness lower down the throat often associated with a hoarse voice. In patients with infectious mononucleosis (glandular fever) requiring hospital admission, corticosteroids may have a role when pain and swelling threaten the airway or where there is very severe dysphagia. Antibiotics confer relative benefits in the treatment of sore throat. SIGN has produced its own criteria for tonsillectomy for children and adults, viz:.
Treatment of psoriasis in children: is there a role for antibiotic therapy and tonsillectomy? Wilson JK, Al-Suwaidan SN, Krowchuk D, Feldman SR. Because these treatments are relatively benign compared to other treatments for severe psoriasis, the use of antibiotic therapy or tonsillectomy may still be worth considering, especially for those patients with recurrent streptococcal infections that seem to trigger or maintain their skin disease. The choice of treatment for psoriasis in children, as in adults, is determined by disease acuity, morphology, distribution, severity, and the presence of comorbidities, such as psoriatic arthropathy. Treatment of psoriasis in children: is there a role for antibiotic therapy and tonsillectomy? Treatment of psoriasis in children: is there a role for antibiotic therapy and tonsillectomy?. The purpose of this article is to review the efficacy of antibiotic therapy and tonsillectomy as treatments for childhood psoriasis.
Macrolides In Chronic Inflammatory Skin Disorders
There is no consensus on the best treatment for guttate psoriasis. Topical therapies commonly used include simple emollient therapy, corticosteroids, tar formulations and, more recently, vitamin D analogues. Antibiotic therapy. McMillin et al found that two children with recurrent streptococcal pharyngitis or tonsillitis complicated by recurrent guttate psoriasis were completely free of psoriasis 16 months after adenotonsillectomy. A role for tonsillectomy in the treatment of psoriasis? Learn more from WebMD about guttate psoriasis and its link to illnesses like strep throat and tonsilitis. Usually there is a fine scale on the drop-like lesion that is much finer than the scales in plaque psoriasis, which is the most common type of psoriasis. Viral infections, such as chicken pox, rubella, and roseola, may also trigger outbreaks in children. Some doctors recommend antibiotic therapy for sore throat in people who are susceptible to guttate psoriasis outbreaks.