All types of nail lesions were prevalent in HLA-Cw0606-negative patients, whereas in HLA-Cw0602-positive patients, nail lesions correlated with psoriatic arthritis. In our open study, 10 10 patients completed 3 months of treatment and presented good response in all ungual lesions (especially onycholysis and subungual hyperkeratosis), with the exception of nail pitting. Tacalcitol in treatment of psoriasis vulgaris: the Spanish experience. Treatment of Nail Psoriasis: Common Concepts and New Trends. Read Treatment of nail psoriasis with 8 clobetasol nail lacquer: positive experience in 10 patients on DeepDyve – Instant access to the journals you need!
We performed an open observational study of 6 patients diagnosed with nail psoriasis. Among PP patients, prevalence of nail psoriasis documented in the literature is over 50, with an estimated lifetime incidence of 80 90 1. Patients with psoriasis can present with multiple levels of involvement and with different types of the chronic condition.
Triamcinolone acetonide 10 mg/ml is the mainstay intralesional agent used bimonthly. Psoriasis localized to certain areas of the body like scalp, nails, palms and soles remains difficult to treat. Topical treatment remains the first line of therapy for patients who present with an isolated involvement of these sites. Importantly, 70-80 of patients with psoriatic arthritis have nail psoriasis. Also, treatment of nail psoriasis is a big challenge for a dermatologist because of the following reasons:Poor drug delivery: the matrix pathology is hidden by the proximal nail fold and the nail bed changes are protected against treatment by the overlying nail plate and nail bed hyperkeratosis, making delivery of drug to the affected site very difficult.
Nail Psoriasis: Treatment With Tazarotene Hydrophilic Ointment
The lifetime incidence of nail involvement in psoriatic patients is estimated to be 80 90, and the nails can be affected in 10 to 55 of psoriatic patients.