Generalised pustular psoriasis is a rare and serious skin disorder that presents with flares of widespread sterile pustules on a background of red and tender skin. It is also known as acute generalised pustular psoriasis of von Zumbusch. See the DermNet NZ bookstore. The acute generalized type is also termed von Zumbusch variant. Pustular psoriasis is primarily seen in adults. It may be limited to certain areas of the body for example, the hands and feet. Generalized pustular psoriasis also can cover most of the body. It tends to go in a cycle with reddening of the skin followed by pustules and scaling.
The acute variant (also known as generalized pustular psoriasis of von Zumbusch) is characterized by sudden onset of the pustular eruption accompanied by systemic symptoms of fever and malaise. Read more about symptoms, signs, causes, and treatment, and see pictures. For generalized pustular psoriasis, systemic agents such as retinoids may be required from the beginning of treatment. A ring-shaped (annular, or circinate) type has also been described. Von Zumbusch Generalized Pustular Psoriasis (GPP) can be life-threatening but is rare. You’ll find pustules with yellow-brown macules on the palms and soles, and scaly red plaques may also be present.
See our Psoriasis and Phototherapy leaflet. In some instances biologic injection treatments may be used, but these are not licensed for pustular psoriasis. ‘Pustular psoriasis’ can refer to two different types of psoriasis with similar names: Pustular Psoriasis of the palms and soles (also referred to as palmoplantar pustulosis or PPP), and Generalised Pustular Psoriasis, which is quite a rare and serious form of psoriasis. See also the symptoms of Generalized pustular psoriasis and Generalized pustular psoriasis: Introduction.
Pustular Psoriasis: Management
Acute generalized pustular psoriasis, von Zumbusch type, treated in the burn unit. We also discuss the latest reports utilizing biological response modifying drugs. Generalized pustular psoriasis: This is a rare form of psoriasis is also known as von Zumbusch psoriasis. See full list of 24 symptoms of Generalized pustular psoriasis. Looking for online definition of psoriasis in the Medical Dictionary? psoriasis explanation free. Generalized pustular psoriasis is also known as Von Zumbusch pustular psoriasis. Looking for online definition of generalized pustular psoriasis of Zambusch in the Medical Dictionary? generalized pustular psoriasis of Zambusch explanation free. See also psoriasis. We describe a patient with acute generalized pustular psoriasis (GPP) treated with the new anti interleukin (IL)-17A antibody, secukinumab, who showed a remarkable response with almost complete resolution of pustulation after the first injection. Infantile generalized pustular psoriasis (von Zumbusch) is a rare form of psoriasis. Here, we report a 3-month-old Taiwanese girl who was treated with Chinese herbal medicine for abdominal fullness starting at 1 month of age. View Record in Scopus.
Generalized pustular psoriasis (GPP) is a life-threatening disease characterized by sudden, repeated episodes of high-grade fever, generalized rash, and disseminated pustules, with hyperleukocytosis and elevated serum levels of C-reactive protein (123260) (summary by Marrakchi et al. For a discussion of genetic heterogeneity of psoriasis, see PSORS1 (177900). Generalized pustular psoriasis of pregnancy is a rare variant of pustular psoriasis, also called as impetigo herpetiformis.