Aminopterin for Psoriasis on ResearchGate, the professional network for scientists. Treatment of psoriasis with folic acid antagonists. Arch Dermatol. 1958;78:200 203. Rees, RB, Bennett, JH, Hamlin, EM et al, Aminopterin for psoriasis. Arch Dermatol. After the double-blind study 11 patients were treated with azaribine in a dose of 100 mg/kg of body weight per day for 12 weeks (study C). REES RB, BENNETT JH: Methotrexate vs aminopterin for psoriasis.
Aminopterin (or 4-aminopteroic acid), the 4-amino derivative of folic acid, is an antineoplastic drug with immunosuppressive properties often used in chemotherapy. Similar congenital abnormalities have been documented with methotrexate, and collectively their teratogenic effects have become known as the fetal aminopterin syndrome. REES, R. B., AND BENNETT, J. H. Methotrexate vs. aminopterin for psoria- sis. Arch.Derm. Once a patient is diagnosed with one NMSC, they are at increased risk for additional cutaneous malignancies. Rees RB and Bennett JH, Methotrexate vs aminopterin for psoriasis.
Guidelines of care for the management and treatment of psoriasis with topical therapies. 5Rees, R.B., Bennett, J.H. Methotrexate vs. aminopterin for psoriasis. R.B. Rees, J.H. Bennett, Further observations on aminopterin for psoriasis J. I.B. Mackay, The treatment of psoriasis with methotrexate Brit. Collins CE, Collins C: Roentgen dermatitis treated with fresh whole leaf Aloe vera. Rees RB, Bennett JH: Methotrexate vs. aminopterin for psoriasis.
Edmudson, W.F., Guy, W.B. Treatment of psoriasis with folic acid antagonist. Arch Dermatol. Rees, R.B., Bennett, J.H., Maibach, W.I. et al, Methotrexate for psoriasis. Rees RB, Bennett JH, Hamlin EM, Maibach HI (December 1964).