Arthritis associated with inflammatory bowel diseases is one of the diseases captured under the umbrella of spondyloarthritis. SpA is a group of inflammatory diseases with overlapping features (e.g. psoriasis, uveitis and IBD) and is linked to Human Leukocyte Antigen (HLA)-B27. Other diseases included in the SpA group are ankylosing spondylitis (AS), undifferentiated SpA, arthritis associated with acute anterior uveitis, psoriatic arthritis, reactive arthritis and idiopathic arthritis. These diseases also include reactive arthritis (previously referred to as Reiter syndrome), inflammatory bowel disease, and psoriatic arthritis. For example, HLA-B27 appears in 80-90 of patients with ankylosing spondylitis. Inflammatory bowel disease (IBD) is a general term for two main bowel diseases: Crohn’s disease and ulcerative colitis. They are comprised of a group of diseases, including ankylosing spondylitis, psoriatic arthritis, reactive arthritis, arthritis associated with IBD, and undifferentiated spondyloarthritis. For example, etanercept is associated with a numerically but not statistically higher risk of IBD flareups in AS patients who also have IBD.
Reactive arthritis is an autoimmune condition that develops in response to an infection. Skin (eg, erythema nodosum, circinate balanitis), nails (dystrophic changes) and mucous membranes (mouth ulcers) may all be affected. Gastrointestinal: some patients have intermittent bouts of abdominal pain and diarrhoea – and show lesions on colonoscopy, similar in appearance to inflammatory bowel disease. Psoriatic arthritis. A heterogeneous group of inflammatory rheumatic diseases with predominant involvement of axial and peripheral joints and enthesitis (inflammation at the site of insertion of tendons and ligaments to bone). Family history: a first-degree or second-degree relative with ankylosing spondylitis, psoriasis, acute iritis, reactive arthritis or inflammatory bowel disease. Disease-modifying anti-rheumatic drugs (DMARDs) – eg, sulfasalazine and methotrexate. Other manifestations involve the hepatopan-creatobiliary system (eg, primary sclerosing cholangitis) as well as the ocular, renal, and pulmonary systems. In addition to IBD-related disease, this category includes psoriatic arthritis, reactive arthritis, and idiopathic ankylosing spondylitis (AS).
Reactive arthritis is conventionally defined as an arthritis that arises following an infection, although the pathogens cannot be cultured from the affected joints. For example, psoriatic arthritis was not widely recognized as a distinct form of arthritis until the 1960s. Arthritis Associated With Inflammatory Bowel Disease (Enteropathic Arthritis – EnA):. This person’s combination of disease features suggests spondyloarthritis, but he or she doesn’t fit into the categories of ankylosing spondylitis, psoriatic arthritis, reactive arthritis, juvenile spondyloarthritis or IBD-associated arthritis. Other SpA diseases include infection-triggered reactive arthritis, some forms of juvenile idiopathic arthritis, arthritis in association with inflammatory bowel diseases (IBD), and some forms of psoriatic arthritis 1, 2.
Reactive Arthritis. Information About Reactive Arthritis
Reactive arthritis is a general term for a form of joint inflammation (arthritis) that develops as a reaction to an infection in another area of the body (i. This group of disorders includes reactive arthritis, ankylosing spondylitis, psoriatic arthritis, undifferentiated spondyloarthritis and spondyloarthritis associated with inflammatory bowel disease. This group of disorders includes reactive arthritis, ankylosing spondylitis, psoriatic arthritis, undifferentiated spondyloarthritis and spondyloarthritis associated with inflammatory bowel disease. In addition to manifesting in typical sites (e.g., extensor surface of the knee), psoriasis can be present as a small patch in the scalp, ears, anal cleft, perineum, or umbilicus. These include inflammatory arthritic diseases associated with IBD and reactive arthritis caused by bacterial or parasitic infections of the digestive tract. Psoriatic arthritis and ankylosing spondylitis (AS) are also conditions that share similar symptoms and causes. Other disease entities of SpA include reactive arthritis, psoriatic arthritis, undifferentiated SpA, and arthritis associated with inflammatory bowel disease (IBD), which includes Crohn s disease (CD) and ulcerative colitis (UC) 1. Learn about reactive arthritis, a chronic, systemic rheumatic disease. Reactive arthritis shares many features with psoriatic arthritis, ankylosing spondylitis, and the arthritis of Crohn’s disease and ulcerative colitis. For example, the HLA-B27 gene is commonly seen in patients with reactive arthritis. More than 80 of patients with psoriatic arthritis have nail dystrophy. Psoriatic skin lesions in reactive arthritis, especially the subform Reiter’s syndrome, and patients can move from one subset to another, for example from undifferentiated spondyloarthritis to ankylosing spondylitis. Reactive arthritis, psoriasis, and inflammatory bowel disease are additional, partly independent, risk factors.
For example, psoriatic arthritis leads to joint deformity in the wrists and hands, but there may also be scaling and changes in the skin (from psoriasis). Arthritis may result from infections (e.g., rheumatic fever, staphylococcal infections, gonorrhea, tuberculosis), metabolic disturbances (e. Joint disease associated with inflammatory bowel disease. Reactive arthritis. As JIA is a diagnosis of exclusion, other causes of joint inflammation (e.g. infections etc) should be excluded. The new classification includes systemic-onset, oligoarticular persitent and extended, polyarticular rheumatoid factor negative and positve subsets, psoriatic arthritis, enthesitis related arthritis and undifferentiated arthritis. Exclusion:- psoriasis or a history of psoriasis in a first-degree relative- arthritis in an HLA B27 positive male beginning after his 6th birthday- history of ankylosing spondylitis, enthesitis related arthritis, sacroillitis with inflammatory bowel disease, reactive arthritis, or acute anterior uveitis in a first degree relative- IgM rheumatoid factor positive on 2 or more occasions at least 3 months apart.