Psoriasis is a common, chronic, relapsing, inflammatory skin disorder with a strong genetic basis. Psoriasis may often appear in the nappy region in infancy and in flexural areas in children. Psoriasis is a chronic dermatosis of genetic origin, often precipitated by an event such as an infection, an injury or psychological stress. Abnormal expression of one or more of these leads to infiltration of psoriatic plaques by Th1 or cytotoxic lymphocytes and subsequent overproduction of certain pro-inflammatory cytokines, particularly tumour necrosis factor alpha (TNF- ), interferon gamma (IFN- ), interleukins 2 and 12. The skin disease may present as one or other form of acute psoriasis, chronic psoriasis or localised to hands and feet. Psoriatic arthritis (PsA) is a chronic systemic inflammatory disorder characterized by joint and entheseal inflammation with a prevalence of 0. Skin psoriasis is a major risk factor for the development of psoriatic arthritis. Psoriasis is a common, chronic inflammatory skin disease most often appearing in the form of well-demarcated, scaly plaques. The common comorbidities include cardiovascular disease, metabolic syndrome, obesity, diabetes, fatty liver disease, inflammatory bowel disease, ophthalmic disease, kidney disease, osteoporosis, depression, and anxiety.
Psoriasis causes skin cells to mature in less than a week. Plaque psoriasis (psoriasis vulgaris), the most common form of the disease, is characterized by small, red bumps that enlarge, become inflamed, and form scales. Named for the Latin word gutta, which means a drop, guttate psoriasis is characterized by small, red, drop-like dots that enlarge rapidly and may be somewhat scaly. Often found on the arms, legs, and trunk and sometimes in the scalp, guttate psoriasis can clear up without treatment or disappear and resurface in the form of plaque psoriasis. Any body surface can be affected, but lesions appear most often on the scalp, knees, and elbows. Psoriasis, which manifests most often as plaque psoriasis, is a chronic, relapsing, inflammatory skin disorder with a strong genetic basis. Plaque psoriasis (see the image below) is rarely life threatening, but it often is intractable to treatment. Well defined, with sharply demarcated boundaries. In children with plaque psoriasis, plaques are not as thick, and the lesions are less scaly. Psoriasis is a chronic inflammatory disorder of the skin, in which the skin produces new skin cells too quickly. In the most common forms of psoriasis, excess skin cells accumulate on the skin surface, resulting in thick patches (plaques) of reddened, inflamed skin covered with silvery white scales.
The most common variety of psoriasis is called plaque-type. Psoriasis is a common inflammatory scaling dermatosis with a bilateral symmetric distribution that may be associated with a seronegative spondyloarthropathy. The typical morphology is a 1-cm or larger well-demarcated red plaque surmounted by white or silvery scales. The pressure-bearing areas of palms and soles are most often affected. Psoriasis (PsO) Is a Chronic Inflammatory Disease of the Skin Inflammation is a tightly regulated, naturally occurring part of the body’s protective response to injury or infection, intended to prevent damage to surrounding tissue.
Acne is most often intially problematic during puberty, with the greatest prevalence in the mid to late teen years. Rosacea is a chronic erythematous inflammation of the cheeks, nose, chin, forehead, and eyelids. The classic lesion is a well-demarcated, raised, red plaque with a white scaly surface. A woman presented with erythematous, pruritic skin patches on her trunk and extremities that were slowly increasing in size and number. Early on, the lesions are often misdiagnosed as more common skin conditions, such as eczema and psoriasis. Atopic dermatitis is a chronic inflammatory skin condition characterized by pruritic, erythematous, and scaly lesions often located on the flexor surfaces. Plaques are typically symmetric and bilateral, well demarcated, and covered by a silvery scale. Chronic plaque psoriasis. Psoriasis is a common skin disorder affecting 2 of the population. Psoriasis is an immune-mediated inflammatory dermatological disorder characterized clinically by erythematous papules and plaques covered with silvery scale due to complex alterations in epidermal proliferation and differentiation. Plaque psoriasis is the most common form of psoriasis, presenting as sharply demarcated, erythematous lesion with flaky silvery-white scales most often involving the extensor surfaces knees, buttocks, elbows and scalp. Psoriasis is a chronic inflammatory skin disease, which can present co-morbidity with other conditions like arthritis, heart disease, etc. The condition is characterized by thick inflammed (red) skin with flaky whitish patches which closely resemble scales. This form of psoriasis i.e. psoriasis vulgaris is the most common. – most common – lesions are well-demarcated, thick, silvery, scaly, erythematous plaque surrounded by normal skin – small erythematous papules enlarge and coalesce into larger inflammatory lesions on the face, scalp, elbows, and knees and at sites of trauma. Lesions appear as a rash or cluster of inflamed and painful vesicles – Increased sensitivity, parasthesias, and mild burning may occur before onset of the lesions. Psoriasis is a common chronic inflammatory skin condition in which patients suffer from mild to chronic plaque skin plaques. Psoriasis is an immune-mediated skin disease appearing in a chronic recurring manner. Well-demarcated erythematous plaques covered by white silvery scales are typically observed on extremities and scalp of patients with psoriasis (Figures 1(a) 1(c)). In practice, treatments of psoriasis are most commonly combined with different agents to achieve synergistic therapy.
Psoriasis comprises red, scaly patches of skin, which usually have very well defined edges, appear covered by silvery flaky surface 1. The most common ages for psoriasis to first appear are in the late teens and in the 50s. This form is very widespread and the eruptions often occur in repeated waves lasting days or weeks.