Skip to content

Psoriasis is a chronic skin disease that is affected by the body’s immune system

Psoriasis is a chronic (long-lasting) skin disease of scaling and inflammation that affects greater than 3 percent of the U.S. population, or more than 5 million adults. They most often occur on the elbows, knees, other parts of the legs, scalp, lower back, face, palms, and soles of the feet, but they can occur on skin anywhere on the body. Psoriasis is a skin disorder driven by the immune system, especially involving a type of white blood cell called a T cell. Autoimmune diseases can affect almost any part of the body, including the heart, brain, nerves, muscles, skin, eyes, joints, lungs, kidneys, glands, the digestive tract, and blood vessels. A type of arthritis associated with psoriasis, a chronic skin disease that occurs when cells in the outer layer of the skin reproduce faster than normal. Psoriasis is an autoimmune disease, meaning that part of the body’s own immune system becomes overactive and attacks normal tissues in the body. The treatment of psoriasis usually depends on how much skin is affected, how bad the disease is (e.g., having many or painful skin patches), or the location (especially the face).

Psoriasis is a chronic skin disease that is affected by the body's immune system 2But in people with psoriasis and psoriatic arthritis, the immune system goes into action even without these invaders. Instead, the immune system fights the body’s own tissues. In psoriatic disease, this battle is waged in the skin and joints. Learn more about psoriasis and why the immune system causes psoriasis to appear on the skin. Plaque psoriasis is one of the most common forms. Psoriasis is an autoimmune disease that causes raised, red, scaly patches to appear on the skin. It typically affects the outside of the elbows, knees or scalp, though it can appear on any location. Pustular psoriasis can occur on any part of the body, but occurs most often on the hands or feet. Replay Video Read the Story. Watch what happens to your body underneath the skin to cause plaque psoriasis.

Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin. These skin patches are typically red, itchy, and scaly. They may vary in severity from small and localized to complete body coverage. It controls genes that affect the immune system or encode skin proteins that are overabundant with psoriasis. PSORS1 is located on chromosome 6 in the major histocompatibility complex (MHC), which controls important immune functions. Conditions reported as accompanying a worsening of the disease include chronic infections, stress, and changes in season and climate. Psoriatic arthritis is a form of arthritis that affects people diagnosed with the skin disorder psoriasis. People with psoriasis experience flare-ups of red, patchy skin or skin lesions. Your immune system is designed to protect you from foreign invaders like viruses and bacteria. Sometimes, the body mistakenly attacks healthy tissue. Psoriasis is a chronic autoimmune disease that inflames areas of skin, causing discomfort, itching, and raised skin lesions. These patches of skin are caused by an abnormally fast turnover of skin cells. This immune system reaction then triggers inflammation throughout your body.

The Immune System And Psoriatic Disease

Psoriasis is a chronic skin disease that is affected by the body's immune system 3Psoriasis causes skin cells to build up on the surface of the skin where they form itchy, red patches and thick scales. Find out what causes psoriasis and how to help your child deal with it. Psoriasis is a long-lasting (chronic) condition that can get better or worse, seemingly at random. It may go away completely before suddenly reappearing. Sometimes that affects their emotions, and some kids may develop low self-esteem and even depression as a result. Strep throat, colds, and other infectious diseases trigger the body’s immune system to respond, making a psoriasis outbreak more likely. Scalp psoriasis. Psoriasis is a chronic, inflammatory disease which can affect the skin, joints and nails. In psoriasis, the immune system is mistakenly activated, which leads to overproduction of skin cells. Skin cells build up too rapidly on the surface of the skin, forming raised, red, scaly patches (called plaques). Psoriasis lesions commonly appear on the scalp, but they can occur anywhere on the body. Psoriasis (say: sor-EYE-uh-sus) is a skin problem that causes areas of red, flaky skin. The body’s immune system responds by sending more blood to the area. The body then makes more skin cells and more white blood cells. Psoriasis occurs when faulty signals in the immune system cause new skin cells to grow too quickly, in days rather than weeks. Individuals with psoriasis are at an elevated risk to develop other chronic immune conditions, such as inflammatory bowel disease and diabetes. In psoriasis, the immune system triggers the immune system to make T cells, a type of white blood cell, that cause skin cells to mature in two to three days. Psoriasis is a chronic skin disorder that causes areas of thickened, inflamed, red skin, often covered with silvery scales. Immune system The immune system plays an important role in the skin changes that occur in psoriasis. In skin affected by psoriasis, immune cells enter the skin through blood vessels and cause the epidermis to grow very rapidly and to stop shedding properly (figure 2). Plaque psoriasis may occur in just a few small areas or may cover a large portion of the body.


Root of psoriasisWith psoriasis, the body’s immune system – which creates inflammation as a natural defense against bacteria, fungus, trauma and other invaders – goes haywire, sending out faulty signals that speed up the growth of skin. Various types of autoimmune disorders can affect the skin, such as psoriasis or scleroderma. Learn about common symptoms of these conditions and others. The body reacts in a variety of ways to autoimmune disorders, which cause a person’s immune system to attack its own tissues. Depending on the condition, an autoimmune disorder can affect a variety of organs, joints and muscles, or other bodily tissues. One tissue that’s commonly affected by autoimmune disorders is the skin. Psoriasis is a chronic skin disorder in which there are sharply defined red patches on the skin, covered by a silvery, flaky surface. The disease activity may wax and wane over time. General features Although most diseases affecting the skin originate in the layers. For example, extensive inflammation of the skin may affect metabolism within other organs and systems of the body, causing anemia, circulatory collapse, disorders of body temperature, and disturbance of water and electrolyte balance in the blood. In chronic forms of eczema or dermatitis the prominent changes are thickening of the epidermis and marked hyperkeratosis (thickening of the outer horny layer of the epidermis). In addition to eczematous changes, persons with atopic dermatitis may also often have diminished, absent, or paradoxical cutaneous vascular reactions to vasodilating and vasoconstricting drugs; impaired immunity to fungal and viral infections; and cataracts in the lenses of the eyes.

Scalp psoriasis: about half of people with chronic plaque psoriasis affecting the skin of their body will also have psoriasis affecting their scalp. Another theory is that the immune system may be overreacting in some way to cause the inflammation. Psoriasis may be classified as mild, moderate or severe depending upon the amount of skin involved and the effect on an individual’s quality of life. Eventually, affected individuals develop a herald patch, which is a single scaly red patch, usually on the back, chest or stomach. Autoimmunity is when the body’s immune system mistakenly attacks healthy tissue for unknown reasons. Psoriasis is a chronic, inflammatory skin disease characterized by dry, reddish (erythematous), thickened patches of skin that are covered with silvery-gray scales. When it affects the spine, psoriatic arthritis most frequently targets the sacrum (the lowest part of the spine). Eczema is term for a group of medical conditions that cause the skin to become inflamed or irritated. The exact cause of eczema is unknown, but it’s thought to be linked to an overactive response by the body’s immune system to an irritant. Chronic Skin Conditions. 3. This chronic disorder affects people of all ages. Psoriasis seems to be inherited. If you have a weakened immune system, you may experience more severe symptoms from psoriasis. The skin redness is very intense and can cover your entire body with a red, peeling rash that can itch or burn intensely. Guttate. Autoimmune diseases affect 23.5 million Americans, and that number is rising. Psoriasis is a chronic inflammatory skin condition the most prevalent autoimmune disease in the U.S. Psoriasis is a chronic skin disorder that causes scaling and inflammation. Psoriasis may develop as a result of an abnormality in the body’s immune system. Inverse psoriasis is a plaque type of psoriasis that tends to affect skin creases.