Although previous studies have examined the association between psoriasis and risk of impaired glucose tolerance and DM, conflicting results have been reported, limited data are available on the impact of psoriasis severity on risk of DM, and nationwide data have not been presented (5 15). Our results, however, are clearly in agreement with previous studies demonstrating a link between chronic inflammatory diseases, including psoriasis and rheumatoid arthritis, and augmented risk of DM (5 7,11 13,32,33,37). No other potential conflicts of interest relevant to this article were reported. Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study. Previous reports have demonstrated an association between psoriasis and other diseases, including heart failure and diabetes, said Dr. Abstract. Background: Previous reports have shown an association between inflammatory diseases such as systemic lupus erythematosus or rheumatoid arthritis and the metabolic syndrome.
The Inflammation Link: Association between psoriasis, diabetes mellitus, and atherosclerosis – A case-control study(JAAD 56: 629-634,April 2007) Background Previous reports demonstrated an association between psoriasis and other diseases including heart failure and diabetes mellitus. Background Previous reports demonstrated an association between psoriasis and other diseases including heart failure and diabetes mellitus. Nowadays, Ps is considered an immune-mediated skin disease, and PsA regarded as a seronegative (rheumatoid factor negative) arthritis. Data including body weight, height, waist circumference, body-mass index, and arterial blood pressure were collected. Recent research reported an association between psoriasis and metabolic disorders such as obesity, dyslipidemia, and type II DM and it is shown that severe psoriasis might be associated with increased mortality rate due to cardiovascular disorders 2, 4 6. Other studies showed an increased frequency of ischemic heart disease, DM, hypertension, and dyslipidemia in patients with psoriasis when compared to controls 13, 14.
BACKGROUND: Previous reports have shown an association between inflammatory diseases such as systemic lupus erythematosus or rheumatoid arthritis and the metabolic syndrome. Multivariate models adjusting for age, gender and smoking status of the patients demonstrated that psoriasis was associated with the metabolic syndrome (OR 1. Com We investigated the incidence and severity of echocardiographic and clinical abnormalities in patients with psoriasis and their relationship to the severity, duration and type of psoriasis and other related factors. Examining the relationship between other chronic diseases or comorbidities, like heart disease, with psoriasis and psoriatic arthritis. An ever-growing body of literature demonstrates a link between psoriasis and certain comorbidities, including heart disease, metabolic disorder and inflammatory bowel disease. The researchers, who report that one-third of adult patients with psoriasis first present in childhood, performed a literature search with the terms comorbidities,’ children’ and psoriasis’ that resulted in five relevant papers. In the last study by Brauchli et al, the researchers reviewed data from the UK General Practice Research Database for evidence of increased rates of diabetes mellitus; as expected, the incidence rate ratio for diabetes mellitus was significantly greater in patients with psoriasis. Identify an association between BMI and presence of NAFLD in people with psoriasis and use it as a predictive index for primary screening of NAFLD in psoriatic patients. Fatty Liver Disease (NAFLD) Among Patients With Psoriasis Resource links provided by NLM:. Several reports have demonstrated a possible association between psoriasis and diabetes mellitus, obesity, hypertension, myocardial infarction, and heart failure. Metabolic syndrome (MS) is a cluster of diabetes mellitus, hypertension, visceral obesity and hyperlipidemia and is thought to be caused by insulin resistance and the presence of a systemic inflammation which is evident by the increased level of inflammatory cytokines like TNF in this group of patients.
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Psoriasis and the risk of incident diabetes mellitus: a population-based study. Recent studies have demonstrated an association between systemic inflammatory diseases such as psoriasis, systemic lupus erythematosus or rheumatic arthritis and the cardiovascular risk factors, including metabolic syndrome4. Previous reports have shown an association between psoriasis and diabetes, hypertension, obesity, myocardial infarction and heart failure3, 5-7. The smoking status and medical problems, including cardiovascular diseases, hypertension, diabetes and hyperlipidemia, were surveyed. The Framingham 10-year risk score13, which was designed to estimate the 10-year risk for major coronary events in adults aged 20 and older and who do not have heart disease or diabetes, was calculated for the patients with psoriasis. Previous studies have reported conflicting positive or negative correlations between psoriasis and chronic obstructive pulmonary disease. The odds ratios of chronic obstructive pulmonary disease in subjects with psoriasis/mild-to-moderate psoriasis were analyzed using the random-effects model, while the odds ratios of chronic obstructive pulmonary disease in subjects with severe psoriasis and current smoking in subjects with psoriasis were analyzed using the fixed-effect model. A progressive but not fully reversible airflow limitation and an inflammatory response in the affected lungs leading to dyspnea and other comorbidities characterizes COPD. (TRX4), in subjects with psoriasis and with type 1 diabetes mellitus. 35 Although the prevalence of left ventricular (LV) systolic dysfunction was reported recently to be higher in patients with RA,37 the extent to which traditional risk factors, including hypertension, diabetes mellitus, and smoking, contributed to this association was not evaluated statistically. Prevalences of aortic and tricuspid regurgitation were not different between RA patients and control subjects undergoing transesophageal echocardiography. 50 patients with psoriatic arthritis and no cardiovascular disease risk factors or clinical disease found prevalences of valvular regurgitation, normal pulmonary artery pressures, and abnormal diastolic relaxation comparable to those in 50 matched control subjects. Aim: To study the association between psoriasis and metabolic syndrome and its components. Materials and Methods: A case-control, hospital-based multicenter study was designed including 173 consecutive psoriatic patients and 184 nonpsoriatic subjects as control during a period of 2 years. Several recent reports have demonstrated a possible association between psoriasis, obesity, hypertension, diabetes and ischemic heart disease. In psoriasis patients, CIMT was associated with hypertension, hypertriglyceridaemia, diabetes, insulin resistance, increased severity and duration of psoriasis while in multivariate analysis insulin resistance (OR 2. We included those patients who were more than 20 years old, disease duration at least six months and were not receiving any systemic treatment for psoriasis at least one month before enrollment. Recent research has demonstrated an association between the systemic inflammatory disease such as rheumatoid arthritis, systemic lupus erythematosus or psoriasis and the cardiovascular risk factors including metabolic syndrome. Recent reports have shown an increased prevalence of diabetes mellitus, obesity, hypertension, dyslipidaemia, myocardial infarction and heart failure in patients of psoriasis.
Psoriasis (Pso) is a common chronic cutaneous inflammatory disease involving the skin that is associated with serious comorbidities. Comorbidities in Pso include psoriatic arthritis (PsA), reduced quality of life, malignancy, depression, but also a constellation of associated conditions that enhance the cardiovascular (CV) risk. This review indicated that traditional CV risk factors were commonly observed in patients with PsA, with an increased prevalence of hypertension, obesity, diabetes mellitus, and dyslipidemia. This study demonstrated a graded positive association between BMI evaluated at multiple time points and the risk of incident Pso.