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Patients with nail psoriasis applied indigo naturalis oil extract on affected nails twice daily for 24 weeks

Patients with nail psoriasis applied indigo naturalis oil extract on affected nails twice daily for 24 weeks. Twenty-five psoriatic patients with nail involvement and mild cutaneous psoriasis were instructed to apply a calcipotriol-betamethasone valerate ointment formulation once daily for 12 weeks on affected nails. The participants applied indigo naturalis oil extract topically to one of two bilaterally symmetrical psoriatic finger nails twice daily for 24 weeks. Indigo naturalis oil extract will be consistently applied on either the left or right affected nail folds, while calcipotriol will be applied on the opposite side, both twice daily for 24 weeks, allowing intra-patient comparison. Patients with nail psoriasis can develop a wide variety of nail ch. 0.1 ointment to the nail folds of affected nails and the contralateral hand was given no treatment 28. At week 24, the mean change in the target nail modified NAPSI score was greater in the certolizumab pegol 200 mg and 400 mg groups than in the placebo group (-1. A 24-week, split-body randomized trial that compared twice-daily application of indigo naturalis extract in oil to twice-daily topical calcipotriol solution (50 mcg/mL) in 33 patients with bilateral fingernail psoriasis found greater improvement in disease severity scores on nails treated with indigo naturalis than in nails treated with calcipotriol 69.

Patients with nail psoriasis applied indigo naturalis oil extract on affected nails twice daily for 24 weeks 2In all participants, indigo naturalis extract in oil was applied to the fingernails of one bilateral hand (experimental group) twice daily for the first 24 weeks. NAPSI for the Single Most Severely Affected Nail of Each Hand at Week 24. Other common forms of psoriasis may affect the scalp, joints, creases, or nails, even in patients without psoriasis of the skin. In a third report, indigo naturalis extract was compared with topical calcipotriol solution 75. Change From Baseline in Single-Hand Nail Psoriasis Severity Index (NAPSI)and in the Modified Target NAPSI for the Single Most Severely Affected Nail of Each Hand at Week 12. This study is an intra-patient side-to-side comparison, it measures nail disease on a single hand. NAPSI for the Single Most Severely Affected Nail of Each Hand at Week 24. Other: Olive Oil Patients were instructed to apply olive oil on one of two bilaterally symmetrical psoriatic finger nails which were different to the INOE side twice daily for first 12 weeks, after that, indigo naturalis oil extract was applied to replace olive oil for another 12 weeks.

Treating nail psoriasis is notoriously difficult and lacks standardized therapeutic regimens. Lindioil (experimental group) or olive oil (control group) was applied topically to the same subjects’ two bilaterally symmetrical psoriatic nails twice daily for the first 12 weeks and then subjects applied Lindioil to both hands for 12 additional weeks. There were no adverse events during the 24 weeks of treatment. This protocol also describes how to assess the patient daily, monitor for adverse effects (including pruritus and burning), and adjust the treatment based on the patient’s response. There were no adverse events during the 24 weeks of treatment. The unsightly appearance of affected nails has a marked impact on the patient’s quality of life (de Jong et al. Beginning with week 13, Lindioil was applied to all affected nails on both hands twice daily for another 12 weeks. The lifetime incidence of nail involvement in psoriatic patients is estimated to be 8090, and the nails can be affected in 10 to 55 of psoriatic patients. On the other hand, when the placebo group was switched to infliximab therapy at week 24, they achieved NAPSI scores comparable to those obtained with the original treatment group 54.

Evaluation Of The Efficacy And Safety Of Indigo Naturalis Oil Extract On Psoriatic Nails

Patients with nail psoriasis applied indigo naturalis oil extract on affected nails twice daily for 24 weeks 3Disclosed herein are an oil-extracted product of indigo naturalis, and the preparation process thereof. The indigo naturalis ointment as previously developed by the applicants has the drawbacks of unpleasant odor and deep blue color that may leave stains on nails, skins and clothes, thereby affecting patients’ compliance. 0.01-1 mg of indirubin), and may be administered once daily or twice daily. Treating nail psoriasis is notoriously difficult and lacks standardized therapeutic regimens. Lindioil (experimental group) or olive oil (control group) was applied topically to the same subjects’ two bilaterally symmetrical psoriatic nails twice daily for the first 12 weeks and then subjects applied Lindioil to both hands for 12 additional weeks. Outcomes were measured using Nail Psoriasis Severity Index (NAPSI) for five nails on one hand and for the single most severely affected nail from either hand. There were no adverse events during the 24 weeks of treatment. Efficacy and safety of Indigo naturalis extract in oil (Lindioil) in treating nail psoriasis: A randomized, observer-blind, vehicle-controlled trial. Lindioil (experimental group) or olive oil (control group) was applied topically to the same subjects’ two bilaterally symmetrical psoriatic nails twice daily for the first 12 weeks and then subjects applied Lindioil to both hands for 12 additional weeks. There were no adverse events during the 24 weeks of treatment. Oil Extract and Calcipotriol Solution in Patients With Nail Psoriasis – Healthetreatment. The participants applied indigo naturalis oil extract topically to one of two bilaterally symmetrical psoriatic finger nails twice daily for 24 weeks. Serum leptin, adiponectin, resistin and ghrelin levels in psoriatic patients treated with cyclosporin. METHODS: Patients with nail psoriasis applied indigo naturalis oil extract on affected nails twice daily for 24 weeks. Only last week did I finish my most recent course of UVA, which only took 5 weeks to clear it up, with 16 UV sessions and coaltar everyday (not the most pleasant). I am really making sure to stay on top of my aftercare this time, as Riscott mentioned, moisturising at least twice a day. Hiya,i had light therepy as an in patient many years ago,treatment was a bath in coaltar,light therapy then wrapped head to toe in thick jelly like cream and wrapped in bandages. I was wondering if people drink alcohol whilst having the treatment or I this hampers the affect UV treatment will have.

Patent Us20120213868

Find patient medical information for ISATIS on WebMD including its uses, effectiveness, side effects and safety, interactions, user ratings and products that have it. Ban Lan Gen, Ban Lang Gen, Baphicacanthus cusia, Chinese Indigo, Clerodendron cyrtophyllum, Da Qing Ye, Da Quing Ye, Dyer’s Woad, Farberwaid (F rberwaid), Folium Isatidis, Gen t des Teinturiers, Gu de, Hierba Pastel, Indigo, Indigo Naturalis, In. Isatidis, Gent des Teinturiers, Gude, Hierba Pastel, Indigo, Indigo Naturalis, In. Isatis is applied directly to the skin for a skin condition, psoriasis. In the current study, Lin and co-workers tested the efficacy of a refined formulation of indigo naturalis extract, designed to reduce blue discoloration of the skin, nails, and clothes, on the nails of 28 patients with nail psoriasis. The participants applied one drop of the extract to the affected nails twice a day for 24 weeks.