Optical coherence tomography imaging of psoriasis vulgaris: correlation with histology and disease severity. Psoriasis Disease severity Histopathology Optical coherence tomography (OCT) Epidermal thickness Psoriasis area and severity index (PASI) Self-administered PASI (SAPASI) Psoriasis life stress inventory index (PLSI) Dermatology life quality index (DLQI). Optical coherence tomography (OCT) is a non-invasive optical imaging technique that uses low-power infrared laser light to image up to 2 mm beneath the skin surface. Optical coherence tomography imaging of psoriasis vulgaris: correlation with histology and disease severity. FULL TEXT Abstract: Optical coherence tomography (OCT) is an emerging noninvasive imaging method that uses infrared light and interferometric techniques. Therefore, the depth of OCT imaging is reduced in hyperkeratotic conditions such as psoriasis. Optical coherence tomography imaging of psoriasis vulgaris: correlation with histology and disease severity.
In our OCT imaging of skin, two different imaging protocols are used based on whether or not a refractive index (RI)-matching medium is applied. Jemec, Optical coherence tomography imaging of psoriasis vulgaris: correlation with histology and disease severity, Arch. Ultrasound aids in diagnosis and severity assessment of hidradenitis suppurativa. The clinical types of psoriasis are correlated with the severity of the disease, and a lesional severity index, such as the psoriasis severity index (PSI), could be used as a quantitative tool for assessing gross severity. Conclusion In the future, subjective gross assessment should be modified by using objective measuring devices with detailed scales, in order to correlate the findings with the histological severity.
Medical and scientific articles about Psoriasis, written by Sren Kamp. 2, Article, Disease quantification in dermatology: in vivo near-infrared spectroscopy measures correlate strongly with the clinical assessment of psoriasis severity. Psoriasis is a chronic inflammatory skin disease characterized by T-cell-mediated hyperproliferation of keratinocytes in the skin. Histopathology of nail psoriasis varies according to the clinical focus of the disease. The capillary density was different in each patient and positively correlated with disease severity. Dense orthokeratosis with compact keratin on histopathology (H&E, original magnification 40), corresponding to white hyperreflective areas on optical coherence tomography. Primary knuckle pads can be sporadic or associated with other conditions such as palmoplantar keratoderma, acrokeratoelastoidosis costa, fibrosing disorders, or Bart-Pumphrey syndrome.4 Secondary knuckle pads, which are more common, occur in sites of repetitive trauma or pressure.
Nelson grade (R20.840) correlated best with dry eye symptom severity. Psoriasis is a chronic autoimmune disease that triggers skin to speed up its cellular growth cycle. Erbagci I, Erbagci Z, Gungor K, Bekir N (2003) Ocular anterior segment pathologies and tear film changes in patients with psoriasis vulgaris. Diabetic retinopathy results in structural changes within the retina that can be observed by OCT imaging, and which correlates with the severity of vision loss.