Neoral is also used to treat psoriasis and rheumatoid arthritis in certain patients. Some patients treated with Neoral have developed severe and sometimes fatal infections, such as progressive multifocal leukoencephalopathy (PML) or severe kidney problems associated with BK virus infection. Cyclosporine is also used to treat severe psoriasis when other treatments have not been effective. Systemic treatments for psoriasis may be taken by mouth or injection. This group of medicines is also a first-line treatment for adults with severe psoriasis.
Psoriatic arthritis is a type of arthritis that causes joint pain, swelling, and stiffness in people with psoriasis. It produces symptoms similar to those of rheumatoid arthritis. Cyclosporine Cyclosporine is a drug that suppresses the immune system and is also used to treat severe psoriasis and psoriatic arthritis. Adding cyclosporine to methotrexate may be more effective than either treatment alone. Information on the treatment options available for Rheumatoid Arthritis from the Johns Hopkins Arthritis Center. Corticosteroids are also useful as chronic adjunctive therapy in patients with severe disease that is not well controlled on NSAIDs and DMARDs. Methotrexate is also effective in many other forms of inflammatory arthritis including psoriatic arthritis and other spondyloarthopathies, and is used in many other autoimmune diseases. Novartis Launches Neoral(R) for Rheumatoid Arthritis; Psoriasis Indication to be Launched Later This. It also was recently cleared for marketing for treatment of severe recalcitrant, plaque psoriasis.
Neoral is also used to treat psoriasis and rheumatoid arthritis in certain patients. Rheumatoid Arthritis: Neoral capsules and oral solution are also indicated for the treatment of severe active rheumatoid arthritis in patients for whom classical slow-acting antirheumatic agents are inappropriate or ineffective. Neoral is also contraindicated in the treatment of psoriasis and rheumatoid arthritis patients under the following circumstances: abnormal renal function; uncontrolled hypertension; malignancy (except nonmelanoma skin cancer); uncontrolled infection; primary or secondary immunodeficiency excluding autoimmune disease. Neoral or Sandimmune I.V. should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Cyclosporin (Sandimmune, Neoral) is used in heart, liver, kidney, pancreas, bone marrow, and heart/lung transplantation. The Neoral form of cyclosporin has been used to treat psoriasis and rheumatoid arthritis. The drug is also used to treat patients with psoriasis. These drugs are very powerful and can cause such serious side effects as high blood pressure, kidney problems and liver disorders.
Immunosuppressant drugs, also called anti-rejection drugs, are used to prevent the body from rejecting a transplanted organ. In addition to being used to prevent organ rejection, immunosuppressant drugs are also used to treat such severe skin disorders as psoriasis and such other diseases as rheumatoid arthritis, Crohn’s disease (chronic inflammation of the digestive tract) and patchy hair loss (alopecia areata). The Neoral form has been used to treat psoriasis and rheumatoid arthritis.