Dr van de Kerkhof has been working for many years on the pathogenesis and treatment of psoriasis. Dr. Menter has a long-held interest in psoriasis and psoriatic disease research. Relevant Terms: psoriasis, psoriatic arthritis Primary Audience: Dermatologists, rheumatologists, primary care physicians, physician assistants (PAs), nurse practitioners (NPs), registered nurses (RNs) and other clinicians managing patients with psoriasis and/or psoriatic arthritis Launch Date: 12-Jun-15 Credits: 0. Alan Menter, MD Chief, Division of Dermatology Baylor University Medical Center Clinical Professor of Dermatology University of Texas, Southwestern Medical School Dallas, TX Alan Menter, MD Dr. Director, Rheumatology Clinical Research Center Los Angeles, CA Daniel Furst, MD Dr. Faculty and course directors have disclosed relevant financial relationships with commercial companies, and the credit providers have a process in place to resolve any conflict of interest. Cynthia Trickett has been a Physician Assistant since 1995 when she graduated with her Bachelor’s of Science in Physician Assistant Studies from the University of Texas Medical Branch, Galveston, TX. She has guest lectured for the National Psoriasis Foundation as well as lecturing to Dermatology practitioners across the United States on psoriatic disease. Psoriasis. Dr. Menter has a long-held interest in psoriasis and psoriatic disease research.
Other types of herbal diet pills act as appetite suppressants. Dr Menter has a long-held interest in psoriasis and psoriatic disease research. Keywords: Acitretin, Biologics, Methotrexate, Psoriasis, Psoriatic nail disease, Severe scalp psoriasis, TNF- inhibitor. In an effort to provide treatment guidance regarding a selected group of complex psoriasis scenarios, individuals with a specific interest in psoriatic disease formed a consensus panel and carried out a Delphi exercise. This Delphi exercise began with the identification of 14 experts in the field of psoriasis by virtue of their publication record, participation in national meetings, interest in treating psoriasis and psoriatic arthritis, and participation in clinical trials and basic research on psoriatic disease. Clinical Research Center, UMDNJ-Robert Wood Johnson Medical School, 51 French St. Over 12 000 patients with psoriasis have been treated with alefacept since its approval in 2003. Lebwohl M, Menter A. The treatment of active psoriatic arthritis with alefacept in combination with methotrexate: a randomized, double-blind, placebo-controlled study.
Psoriasis is a chronic, proliferative, and inflammatory skin disease affecting 2-3 of the population and is characterized by red plaques with white scales. Psoriasis has been long thought to be caused by hyperproliferation of keratinocytes. Psoriatic patients on biologics show greater improvement than do patients on topicals, phototherapy, or conventional systemic agents, and both patients and their dermatologists express greater satisfaction with these biological therapies 20. Research continues to elucidate new pathological mechanisms and develop new oral agents including Janus kinase (Jak), protein kinase C (PKC), and mitogen-activated protein kinase (MAPK) inhibitors (Figure 2). Psoriatic arthritis (PsA) is an inflammatory seronegative spondyloarthropathy associated with psoriasis. Long-term consequences of untreated PsA include persistent inflammation, progressive joint damage and, in many cases, substantial functional limitations, pain and disability. Competing interests statement. Guidelines of care for the treatment of psoriasis and psoriatic arthritis: Case-based presentations. Funding of guideline production by medical or pharmaceutical entities is prohibited, full disclosure is obtained and updated for all work group members throughout guideline development, and guidelines are subject to extensive peer review by the AAD Clinical Guidelines and Research Committee, AAD members, the AAD Council on Science and Research, and the AAD Board of Directors. 3 JAM ACAD DERMATOL Menter et al 3 significant deforming disease, has been reported to occur in up to 42 of individuals with psoriasis (Guidelines, Section 2). 58 A more recent explanation for the perceived tachyphylaxis observed in the clinical setting is poor patient adherence rather than the long-held view of down-regulation of receptor function as the major cause.
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K. Papp Clinical Research, like many high-enrolling research sites, has had routine inspections by the Food and Drug Administration, Health Canada, and the European Medicines Agency. An author on over 275 publications, and a highly sought-after speaker known for delivering engaging, thought-provoking and accessible presentations, Dr. Papp is held in the highest esteem by the academic and medical communities. Papp KA, Menter MA, Abe M, Elewski B, Feldman SR, Gottlieb AB, Langley R, Luger T, Thaci D, Buonanno M, Gupta P, Proulx J, Lan S, Wolk R; OPT Pivotal 1 and OPT Pivotal 2 investigators. This concise handbook looks at psoriasis and psoriatic arthritis as separate but often related conditions, focusing on a background around the indications, such as disease overview and epidemiology; going on to look at the etiology and immunopathogenesis of each indication; looking at the clinical presentation and diagnosis; before focusing on the current and emerging treatment options, including a brief section on the issues of quality of life and comorbidities associated with these indications. By using the Web site, you confirm that you have read, understood, and agreed to be bound by the Terms and Conditions. Treatment of both diseases is typically driven by disease severity. Keywords: psoriasis, psoriatic arthritis, etanercept, biological therapy, tumor necrosis factor, safety. Dario Kivelevitch, Bobbak Mansouri, Alan Menter Department of Dermatology, Baylor University Medical Center, Dallas, TX, USA Abstract: Psoriasis is a chronic, immune-mediated inflammatory disease affecting both the skin and joints. Dr. Martin Alan Menter – Dermatologist at Texas Dermatology Associates, PA (Dallas, TX). He completed his dermatology residency at Pretoria General Hospital at the University of Pretoria, also in South Africa, and two fellowships in London at Guy’s Hospital and St. John’s Hospital for Diseases of the Skin. Since then, he has held several positions within the UT and Baylor University systems. In 2007, he was appointed director of the Baylor Research Center and in 2010, Program Director of the newly formed Dermatology Residency Program at Baylor University Medical Center. A. S. Kourosh, BS1; A. Miner, BS1; A. Menter, MD1,2 1The University of Texas Southwestern Medical School, Dallas, TX, USA 2Division of Dermatology, Baylor University Medical Center, Dallas TX, USA. These conditions share etiologic features and health consequences that directly correlate with the severity of psoriatic disease. Patients who are obese, and those who have severe psoriasis, often share a common psychological experience. 4,6 A growing body of research suggests that these diseases may in fact share an etiologic link, which may permit them to join atherosclerosis, autoimmune disease, and other comorbid conditions as facets of a larger systemic disorder of inflammation.