In addition, vitamins have a role in the immune system, which extends to both innate and adaptive immune responses. Although some vitamins, such as vitamins C and E and members of the B complex, can act in a relatively nonspecific manner in the immune system (for example, as antioxidants)2 4, other vitamins, such as vitamins A and D, can influence the immune response in highly specific ways (see Supplementary information S1 (table)). Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin. Combination therapy with vitamin D and a corticosteroid was superior to either treatment alone and vitamin D was found to be superior to coal tar for chronic plaque psoriasis. Additional monoclonal antibodies have been developed against pro-inflammatory cytokines interleukin-12, interleukin-23 and interleukin-17 79 and inhibit the inflammatory pathway at a different point than the anti-TNF- antibodies. In addition vitamins have also been used to treat psoriasis specifically vitamins A and E. Much of the problem when treating psoriasis is acknowledging the fact that this is a medical condition.
For thousands of years, liver has been used as a cure for night blindness but it was only in the early part of the 20th century that researchers discovered that it is a rich source of vitamin A, which is essential for healthy eyes. Because of its widespread use, Funk’s term continued to be applied, but the final letter e was dropped. In addition dietary Vitamin A, in the form of beta carotene, an antioxidant, may help reduce the risk of certain cancers. The vitamin can also ease alcohol withdrawal symptoms, fight bronchitis, reduce the risk of high blood pressure and reduce acne. WebMD provides a list of natural remedies used to treat Psoriasis. Considering taking a vitamin or supplement to treat Psoriasis? This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. See additional information. Vitamins A C and E: Vitamin A is an antioxidant that is necessary in many different ways including for healthy skin sight and bones. In addition vitamins have also been used to treat psoriasis specifically vitamins A and E.
Research has suggested that stress can trigger specific immune factors associated with psoriasis flares. Because these drugs are also used to treat psoriasis, this rebound effect is of particular concern. Vitamin A derivatives (drugs related to vitamin A) have been associated with birth defects and should not be used by women who are pregnant, who wish to conceive, or who are nursing. In addition, combinations may allow for lower doses of radiation or medications to be used, minimizing side effects. Vitamins A, D, C, and E have been used in a variety of skin care products and may provide healthful benefits and treatment. Vitamin D Vitamin D is another nutrient that has been shown to be effective for treating harsh skin conditions, specifically psoriasis. Vitamin C is best known for its antioxidant properties, although it also plays a role in collagen synthesis. In addition, like vitamin C, vitamin E is more concentrated in the epidermis than in the dermis, suggesting similar effects on the epidermis’ appearance. Retinoids have also been reported to induce this condition.
Free E-newsletter. These synthetic forms of vitamin D slow down the growth of skin cells. Anthralin (Dritho-Scalp) also can remove scale, making the skin smoother. These are commonly used to treat acne and sun-damaged skin, but tazarotene (Tazorac, Avage) was developed specifically for the treatment of psoriasis. Currently, calcineurin inhibitors tacrolimus (Prograf) and pimecrolimus (Elidel) are approved only for the treatment of atopic dermatitis, but studies have shown them to be effective at times in the treatment of psoriasis. It specifically has a role in cellular proliferation, differentiation, apoptosis, and angiogenesis 1. In addition, cytokines and FFA in metabolic syndrome also increase the liver production of fibrinogen and PAI-1. Vitamin D has been used to treat psoriasis in the topical form with great success 24, 25. Sometimes, the nails are also affected with Psoriasis. There may be seen thickened areas with silvery scales, often in the scalps, elbows, knees and lower back. Sea Buckthorn has been used to treat skin disorders in Eastern medicine for centuries and is now being touted as a natural remedy in an effort to treat periodic psoriasis flare-ups. In addition, Sea Buckthorn oil has antibacterial, anti-inflammatory and regeneration-promoting properties, and contains essential fatty acids and tocopherols – vital for maintaining healthy skin. Because of its high levels of Vitamins A and E, essential fatty acids and flavonoids, research indicates that Sea Buckthorn oil may:. A preparation of 10 tar in a fatty-acid based lotion can also be effective. Combining a corticosteroid and vitamin D analog may offer additional benefit; Other topical therapies used for psoriasis (eg, tazarotene, coal tar shampoo, anthralin) and intralesional corticosteroid injections also may be beneficial for scalp involvement, though data on efficacy specifically in scalp disease are limited 10. Many agents used in the treatment of adult psoriasis have also been used for children 16. Specifically, the T.R.U.E. test screens for 44 distinct allergens and the Balsam of Peru (myroxylon perierea) mixture. This fat-soluble vitamin has been frequently used in topical medications and cosmeceuticals due to its antioxidant properties. Alpha-tocopherol has also been purported to prevent cataracts, slow the progression of Alzheimer’s disease, and decrease the rate of certain cancers, including prostate. Vitamin E has shown minimal efficacy in a limited number of conditions as demonstrated by double-blind controlled studies, some of which include yellow nail syndrome and melasma.10,11 Vitamin E has been used to treat other conditions for which there are mixed claims of its effectiveness.
Fish oil may also be effective as a complement to other therapies. In fact, specific 1-alpha-hydroxylase mutations can cause vitamin D-specific rickets (Miller 2000). In a placebo-controlled clinical trial in psoriasis patients, the addition of 50 mg of pycnogenol three times daily to standard treatment resulted in significant improvement in skin redness, hardening, and scaling compared with standard treatment alone (Belcaro 2014). The peony plant has been widely used in traditional Asian medicine to treat autoimmune diseases (He 2011; Wang, Zhang 2014). Circulating calcitriol is also adversely affected by a reduced number of viable nephrons, high serum concentrations of fibroblast growth factor-23, and high levels of inflammatory cytokines such as interleukin (IL)-1, IL-6, and tumor necrosis factor-alpha (TNF- ) 19 and 21. Psoriasis is a skin disease that is characterised by the development of red patches that are covered over with silvery-white scales. Whilst the advice below is based on scientific clinical studies, it is not considered a substitute for medical treatment, and we recommend that sufferers consult their Doctor. A multivitamin can help to redress such a deficiency, providing important minerals such as beta carotene, vitamin B12 vitamin C and vitamin E which have been shown to help. A release of toxins into the system is not sensible unless we also provide additional support for the body to detoxify these substances and facilitate their removal from the body. Psoriasis treatments with medical marijuana and cannabis, research information.
There are five main types of psoriasis, each of which has specific symptoms:. Psoriasis can also cause psoriatic arthritis, which results in pitted, discolored nails and swollen, painful joints. Topical options include steroids, vitamin D analogues, topical retinoids, and coal tar. Oral drugs used to treat severe or stubborn psoriasis include retinoids, cyclosporine, methotrexate, hydroxyurea, and other immunomodulators.