In addition to its morbidity and severe discomfort, erythrodermic psoriasis also may be potentially life-threatening. We present demographic, clinical, and laboratory findings of 50 patients with psoriatic erythroderma seen at our day-care center during a 9 1/2-year period. 1. Dallas, Texas, USA. 1From the Psoriasis Center, Baylor University Medical Center. In addition to its morbidity and severe discomfort, erythrodermic psoriasis also may be potentially life-threatening. We present demographic, clinical, and laboratory findings of 50 patients with psoriatic erythroderma seen at our day-care center during a 9 -year period. Drugs may also precipitate or exacerbate the disease including lithium, quinidine, clonidine, iodine, indomethacin, some beta-blockers, terfenadine, NSAIDS, ACE inhibitors, interferon-alpha, interleukin-2, isotretinoin, and antimalarial agents. BACKGROUND: Psoriasis is a common disease with substantial effects on quality of life. In addition to its morbidity and severe discomfort, erythrodermic psoriasis also may be potentially life-threatening.
More severe psoriasis may be treated with phototherapy, or may require systemic therapy. 2 Individualized and carefully monitored therapy can minimize morbidity and enhance quality of life. Smoking increases the risk of psoriasis and its severity.1,4 Obesity and alcohol use and abuse are also associated with psoriasis. Approximately 90 percent of affected patients have plaque psoriasis, characterized by well-defined round or oval plaques that differ in size and often coalesce6 (Figure 1). Plaque psoriasis (see the image below) is rarely life threatening, but it often is intractable to treatment. Skin biopsy can confirm the diagnosis of plaque psoriasis. Systemic therapy should also be considered for patients with very active psoriatic arthritis, as well as for patients whose disease is physically, psychologically, socially, or economically disabling. Mortality and morbidity. Severe forms of psoriasis such as erythrodermic and generalized pustular psoriasis can be life-threatening and may require urgent treatment in hospital. It also occurs in lichen planus, but not in eczematous dermatoses.
This report summarizes the epidemiology of zoster and its sequelae, describes the zoster vaccine, and provides recommendations for its use among adults aged 60 years in the United States. Additional pain control can be achieved in certain patients by supplementing antiviral agents with corticosteroids and with analgesics. It also was partially efficacious at reducing the severity and duration of pain and at preventing PHN among those developing zoster. Cutaneous dissemination is not life-threatening; however, it is a marker for VZV viremia that can seed the lungs, liver, gut, and brain and cause pneumonia, hepatitis, encephalitis, and disseminated intravascular coagulopathy in 10 –50 of episodes. Other Co-morbidities. Treatment options for moderate to severe psoriasis include topical and systemic medications, phototherapy, and excimer laser. Its long term safety profile continues to be studied, but results so far are positive. The most common type is called plaque psoriasis, also known as psoriasis vulgaris. The severity of psoriasis ranges from one or two flaky inflamed patches to widespread pustular psoriasis that, in rare cases, can be life threatening. Patients with erythroderma require immediate attention as they may face a variety of medical complications. Early detection and effective management of these complications significantly reduce mortality and morbidity of this potential dermatologic emergency. Persons with erythroderma may be medically stable with a subacute or chronic course or alternatively have an acute or even life-threatening onset. They also observed that all patients with psoriatic erythroderma in their study group had a relapse.
Psoriasis may occur at any age, from infancy to the 10th decade of life. The severity of the disease is associated, in part, with the degree of plaque elevation, erythema, and scale present on lesional skin. There are two variants of psoriasis associated with high morbidity and that can be fatal, generalized pustular psoriasis and erythrodermic psoriasis. This myocardial scarring also puts the person at risk for potentially life-threatening abnormal heart rhythms (arrhythmias), and may result in the formation of a ventricular aneurysm that can rupture with catastrophic consequences. C In assessing the severity of skin pain, consider the location; involvement of the eyes, perineum, and hands are associated with greater morbidity. True erythroderma can be life-threatening and must always be considered a dermatologic emergency. Clinical presentation and psoriasis severity may also contribute to variation in prevalence and incidence numbers 3. The condition is extremely rare in children and can be life-threatening because of severe hypothermia, hypoalbuminemia and cardiac failure 17, 32. In addition to the clinical features described above, children often present with a thinner surface scale compared with adults. The erythrodermic psoriasis (EP) is a rare but severe form of psoriasis that may be potentially life-threatening. To study the characteristics of this severe form of psoriasis. Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma. Furthermore, the close proximity of the gingiva to alveolar bone tissue enables also studying bone remodeling under inflammatory conditions. The method described in this work could facilitate gingival analysis, which hopefully will increase our understating on the oral immune system and its role during periodontal diseases. Can not intubate, can not ventilate (CICV) is a potentially life threatening situation.
Prevention Of Herpes Zoster Recommendations Of The Advisory Committee On Immunization Practices (acip)
Blepharitis can be acute or chronic and can occur at all ages but the most commonly encountered variant is chronic adult disease. Demodex mites may also be a causative factor for both anterior and posterior blepharitis. Eyes are sore or gritty. Referral for slit lamp examination would be appropriate where there are severe or resistant symptoms, or where there are signs of other eye disease. Dermatoses – eg, psoriasis, ichthyosis, erythroderma.