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Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis

A crude population measure of obesity is the body mass index (BMI). In addition, adipose tissue can exert both endocrine and immune effects on multiple other organs through the release of adipocytokines 3, which are suspected to contribute to the pathogenesis of several inflammatory conditions, including rheumatoid arthritis (RA) 4. Clinical data from a cohort of 111 Japanese patients treated with ustekinumab 45 mg between July 2011 and March 2014 were retrospectively evaluated. Psoriasis Ustekinumab Obesity Body mass index Psoriasis area and severity index. Department of Dermatology, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-Ku, Tokyo, 105-8641, Japan. However, increased body mass index (BMI) appears to adversely affect responses. It might therefore be valuable to include BMI as a stratification variable in future studies of psoriasis therapies and to consider a patient’s weight or BMI when selecting a systemic psoriasis treatment.

Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis 2Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis. Diet and psoriasis, part I: Impact of weight loss interventions. Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis: evidence from the Psocare project. Psoriasis and body mass index on ResearchGate, the professional network for scientists.

Results: HCPs underestimated the BMI of severely obese people by an average of 22 to 39. (2007) Diagnosis of obesity by primary care physi- cians and impact on obesity management. (2008) Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis. Results: HCPs underestimated the BMI of severely obese people by an average of 22 to 39. (2007) Effects of bariatric surgery on mortality in Swedish obese subjects. (2008) Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis. Obesity and the metabolic syndrome in pediatric psoriasis. S. et al, Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis. Obesity and psoriasis: Body weight and body mass index influence the response to biological treatment.

Diet And Psoriasis: Part I. Impact Of Weight Loss Interventions

Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis 3Greater psoriasis severity and lower response to treatment have been linked to obesity. Psoriasis has been recently established to be a systemic disease centered on inflammation and involvement of cytokines of the Th1 pathway. Impact of body mass index and obesity on clinical response to systemic treatment for psoriasisL Naldi, A Addis, S Chimenti, A Giannetti, M Picardo, C Tomino,. 392014Metabolic abnormalities associated with initiation of systemic treatment for psoriasis: evidence from the Italian Psocare Registry. Keywords: psoriasis, epidemiology, risk factors, treatment. Moderate and severe psoriasis are treated with combined topical and systemic therapy. Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis. Severity of Psoriasis and Body Mass Index: The Cut off are Overweight Patients rather Than Obese Ones, Journal of Clinical & Experimental Dermatology Research. Not only obesity may be associated with higher psoriasis incidence and activity, and prevalence of obesity-related syndromes, but it may also influence the therapeutic approach to disease and the clinical response to systemic treatment, in fact, for a variety of reasons, obese persons with psoriasis are often more difficult to treat 6. (2005) Impact of obesity and smoking on psoriasis presentation and management. The effect of a hypoenergetic diet on psoriasis has not been investigated. Collected data included age, sex, weight, height, BMI, age of psoriasis onset, type and severity of psoriasis, and concomitant medications. Moreover, in these patients, psoriasis relapsed and the patients were switched to other systemic treatments. The clinical response to low-dose cyclosporine in our study was particularly impressive when compared with the published data.

Body Mass Index Estimation And Measurement By Healthcare Professionals