Generalised pustular psoriasis is a rare and serious skin disorder that presents with flares of widespread sterile pustules on a background of red and tender skin. Previously known as impetigo herpetiformis, this name is no longer favoured because the eruption has nothing to do with either impetigo (a bacterial infection) or herpes simplex (a viral infection). Impetigo herpetiformis (IH) is a rare pustular form of psoriasis in pregnancy, associated with constitutional symptoms and complications of secondary infection and sepsis and an increased risk of fetal abnormalities and stillbirths. Case 1:- A 22 year old primigravida, presented at 24 weeks of gestation, with history of generalized pustular eruption for two weeks. It is unclear whether impetigo herpetiformis is a separate entity from generalized pustular psoriasis (GPP). Many women who develop impetigo herpetiformis have no personal or family history of psoriasis and are never symptomatic outside of pregnancy.
Several clinical variants of pustular psoriasis exist: generalized pustular psoriasis (von Zumbusch type), annular pustular psoriasis, impetigo herpetiformis, and two variants of localized pustular psoriasis (1) pustulosis palmaris et plantaris and (2) acrodermatitis continua of Hallopeau. Psoriasis pustuleux gnralis gravidique (Imptigo herptiformis). Proposed diagnosis. Generalized pustular psoriasis of pregnancy (Impetigo herpetiformis). Generalized pustular psoriasis (GPP) presents as an acute or subacute, widely distributed eruption of pustules arising on inflamed, erythematous skin (picture 1A-C).