Impetigo herpetiformis is a rare dermatosis of pregnancy with typical onset during the last trimester of pregnancy and rapid resolution in the postpartum period. In June 2012, a woman was referred by the attending physician of her city of origin for obstetric care in our hospital, 37 weeks pregnant and with skin lesions. Hence, PPG is assumed to be a simple variant of generalized pustular psoriasis, representing a pustular stage of the disease, as a result of the hormonal changes of pregnancy or other factors that are not yet understood. Generalized pustular psoriasis (GPP) is an extremely rare type of psoriasis that can present in a variety of forms. Unlike the most general and common forms of psoriasis, GPP usually covers the entire body and with pus-filled blisters rather than plaques. Sometimes all or any of GPP is referred to as von Zumbusch psoriasis, but in the literature it is often distinguished as one specific form of GPP. It also may or may not recur periodically. Generalized pustular psoriasis of pregnancy is a rare variant of pustular psoriasis, also called as impetigo herpetiformis. The disease in its severe and longstanding form has its impact on fetal outcome by causing placental insufficiency resulting in still birth, neonatal death or fetal abnormalities.
Impetigo herpetiformis is a variant of pustular psoriasis that occurs during pregnancy. There may be some overlap with a pustular drug eruption called acute generalized exanthematous pustulosis. You’ll find pustules with yellow-brown macules on the palms and soles, and scaly red plaques may also be present. The major clinical variants of generalized pustular psoriasis (GPP) include acute GPP (also known as generalized pustular psoriasis of von Zumbusch) and generalized annular pustular psoriasis (also known as subacute GPP) 1. Pregnant women generally observe a mild generalized hyperpigmentation of the nipples, the areolae, and the vulva. Pregnancy results in a decrease in activity of the apocrine glands, with possible improvement of such conditions as hidradenitis suppurativa, which can also be called acne inversa. Impetigo herpetiformis is an acute eruption of pustular psoriasis during pregnancy (most often presenting in the third trimester) in individuals with no prior history of psoriasis.
1) and the in- guinal and genitofemoral area. The erythematosquamous plaques were bordered by tiny pustules in a herpetiform. Pregnant women can suddenly develop a severe generalized pustular eruption resembling generalized pustular psoriasis (GPP). Called impetigo herpetiformis. Normal hormone changes during pregnancy may cause benign skin conditions including striae gravidarum (stretch marks); Preexisting skin conditions (e.g., atopic dermatitis, psoriasis, fungal infections, cutaneous tumors) may change during pregnancy. (e.g., melasma, intrahepatic cholestasis of pregnancy, impetigo herpetiformis, pruritic folliculitis of pregnancy). Erythematous follicular papules and sterile pustules on the abdomen, arms, chest, and back.
Pustular Psoriasis Can Be Life-threatening
Impetigo herpetiformis, also called pustular psoriasis of pregnancy, is a rare pustular dermatosis typically seen in the third trimester of pregnancy. It is unclear whether impetigo herpetiformis is a separate entity from generalized pustular psoriasis (GPP). A. Generalized pustular psoriasis: Generalized pustular psoriasis during pregnancy is also referred to as impetigo herpetiformis.