This paper reviews the epidemiology and clinical features of psoriasis and its impact of patients’ quality of life. Stigmata of psoriasis 16. 4. Classifying psoriasis: The clinical spectrum. 4.1. Chronic plaque psoriasis. Localized plaque psoriasis. Figure 1. The epidemiology, clinical features, and impact on quality of life of psoriasis are reviewed.
Psoriasis is a chronic skin disorder that causes areas of thickened, inflamed, red skin, often covered with silvery scales. The skin is made up of several layers (figure 1). On the one hand, research into its pathogenesis has furthered our general understanding of T cell-mediated autoimmune disorders, and, on the other hand, psoriasis is used increasingly as a primary target disorder for novel therapies that are pathogenesis-oriented (Gottlieb, 2005; Sch n and Boehncke, 2005). Clinical Features: the Many Faces of Psoriasis. (Koebner phenomenon), other causes of cutaneous injury such as viral exanthems or sunburn may elicit the formation of any type of psoriatic lesion.
Pathogenesis and clinical features of psoriasis. Thumbnail image of Figure 1. Figure 1. Single plaque of psoriasis, well demarcated and heavily scaled. Figure: 1. Large plaque psoriasis. Large plaques and confluent areas where lesions have merged. In this presentation, we report a case of a psoriatic woman who developed unusual multiple polypoid lesions approximately 15 cm in size arising from both left and right labia minora and unique connection of FEPs with psoriasis disease.
Correlations between scoring tools used to assess severity of Pso and PsA are shown in Figure 1. The aim of the present study was to describe the clinical characteristics of a population of psoriatics sampled from a patient organisation and not from hospitals or out-patient clinics. Psoriasis causes a high degree of morbidity and decreased quality of life, largely due to clinical flare-ups and disfiguring lesions in visible areas of the skin, systemic manifestations and drug-related side effects. Figure 1 Clinical presentation of severe plaque psoriasis (A) and histochemical staining of a plaque biopsy (B) (A) Clinical presentation of a patient with severe plaque psoriasis, the commonest form of psoriasis. Figure 1. Upper: comparison of clinical features seen in psoriasis and atopic dermatitis. Lower: histopathology of skin (medium power view) from (A) healthy normal control, (B) individual with psoriasis (psoriasiform epidermal hyperplasia with thinning of the suprapapillary plate and the inflammation within the dermal papillae) and (C) an individual with atopic dermatitis (irregular acanthosis, focal spongiosis and mild inflammation within the dermis and epidermis). Figure 1: Clinical manifestation of psoriasis. (A) The red boxes show the most prevalent sites where psoriasis affects the skin. (B) Schematic view of the skin structure of a healthy and a psoriatic patient. The diagnosis of psoriasis, already remarkably expressed in the father’s family in three cases of fraternal twins, could be enforced for several points.