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Evidence grading of clinical studies of Chinese herbal medicine for psoriasis vulgaris

The combination of a Chinese herbal medicine (CHM) bath and narrowband ultraviolet B (NB-UVB) improved the efficacy of NB-UVB treatment of psoriasis vulgaris, but bath therapy is inconvenient. A systematic review, meta-analysis, risk of bias assessment and the GRADE assessment were conducted in accordance with Cochrane Collaboration methodology to assess the evidence for efficacy outcome. The Psoriasis Area Severity Index (PASI) was used in clinical trials for outcome measurement following psoriasis treatment. The combination of a Chinese herbal medicine (CHM) bath and narrowband ultraviolet B (NB-UVB) improved the efficacy of NB-UVB treatment of psoriasis vulgaris, but bath therapy is inconvenient. Randomized controlled trials (RCTs) comparing the combination of orally administered CHM and NB-UVB with that of CHM placebo and NB-UVB or NB-UVB alone for treating psoriasis vulgaris and reporting Psoriasis Area Severity Index (PASI) outcomes were included. A systematic review, meta-analysis, risk of bias assessment and the GRADE assessment were conducted in accordance with Cochrane Collaboration methodology to assess the evidence for efficacy outcome. Print. Abstract and Introduction; What Is the Evidence? Add-on effect of chinese herbal medicine bath to phototherapy for psoriasis vulgaris: a systematic review.

Evidence grading of clinical studies of Chinese herbal medicine for psoriasis vulgaris 2Evidence-Based Complementary and Alternative Medicine (eCAM) is an international peer-reviewed, open access journal that seeks to understand the sources and to encourage rigorous research in this new, yet ancient world of complementary and alternative medicine. Chinese herbal medicine (CHM) bath combined with phototherapy has been used in clinical settings, but the additional benefit requires evaluation. Psoriasis vulgaris (or plaque psoriasis) is the most common clinical manifestation of psoriasis, affecting approximately 80 to 90 of psoriasis patients 1, 4, with its main characteristic being erythematosquamous plaques at certain sites 1, 4. However, the definition of these levels varied across studies. Before treatment for psoriasis can be initiated, the grading and severity must be determined (Table 4). As an anecdote, the recommendation for patients with psoriasis who are using natural light should try to achieve only 5 to 10 minutes spent unprotected in the mid-day sun 3 times per week. According to some studies, many of the original clinical trials conducted using adalimumab and etanercept in patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, and psoriasis showed a 3-fold higher rate of lymphoma compared with the general US population. Underuse of Primary Care in China: The Scale, Causes, and Solutions. The aim of this study was to examine how different levels of yoga involvement are related to different parameters of mental health and illness. Oral Chinese herbal medicine in combination with phototherapy for vitiligo: A systematic review and meta-analysis of randomized controlled trials June 2016. To critically appraise and evaluate the evidence from randomized clinical trials (RCTs) examining the effectiveness of oil pulling on oro dental hygiene. Terms referring to psoriasis vulgaris in the classical Chinese medicine literature: a systematic analysis April 2016.

Medical treatment for psoriasis includes applications of topical steroids and peeling agents that expose the underlying skin for the steroid to contact. Evidence from two double-blind, placebo-controlled trials and one comparative trial suggest that cream made from the herb Oregon grape ( Mahonia) may help reduce symptoms of psoriasis, although it does not seem to be as effective as standard medications. Another small study suggested that the Chinese herbal decoction Qinzhu Liangxue may be helpful in selected patients with psoriasis, though this finding is highly preliminary. Evidence-based practice guideline of Chinese herbal medicine for psoriasis vulgaris (Bai Bi). Systematic reviews and randomized controlled trials of Chinese herbal medicine treating adults with psoriasis vulgaris were evaluated. Risk of bias tool in the Cochrane Handbook and evidence strength developed by the GRADE group were applied for the evaluation, and recommendations were based on the findings incorporating evidence strength. Conclusion: CHM therapy alone or combined with other conventional treatment reported in clinical studies together with expert consensus were recommended for clinical. Outcomes Measured All randomized clinical trials of serum cholesterol reduction, in which mono-preparations of herbal medicinal products were administered as supplements to human subjects, were included. Guggul (Commiphora mukul), fenugreek (Trigonella foenum-graecum), red yeast rice, and artichoke (Cynara scolymus) have been most extensively studied and have demonstrated reductions in total serum cholesterol levels of between10 and 33. A systematic review Objectives To systematically review the clinical evidence for herbal medicinal products in the treatment of hypercholesterolemia.

Add-on Effect Of Chinese Herbal Medicine Bath To Phototherapy For Psoriasis Vulgaris: A Systematic Review

Evidence-based practice guideline of Chinese herbal medicine for psoriasis vulgaris (Bai Bi). Risk of bias tool in the Cochrane Handbook and evidence strength developed by the GRADE group were applied for the evaluation, and recommendations were based on the findings incorporating evidence strength. Zhang’Evidence-based medicine evaluation of randomized controlled clinical trials of TCM for psoriasis vulgaris’China Journal of Leprosy and Skin Diseases, 4 (2003), pp. On the other hand, multiple more-recent clinical studies did not show an increased risk of cancer from Goeckerman treatment, even in those using crude coal tar for long periods of time (van Schooten 1996; Pittelkow 1981; Roelofzen 2010). The spice turmeric has been used as an herbal remedy in traditional Chinese and Ayurvedic medicine for thousands of years. Oral curcumin (Meriva) is effective as an adjuvant treatment and is able to reduce IL-22 serum levels in patients with psoriasis vulgaris. Evidence-based Medicine relies on a Research Hierarchy, because not all evidence is created equal. Systematic reviews of the highest-quality evidence from global clinical trials. Founded in 2000, Natural Standard assigns a grade to each CAM therapy, reflecting the level of available scientific data for or against the use of each therapy for a specific medical condition. Severity of psoriasis was classified as mild, moderate, or severe. All the Chinese clinical trials cited in the manuscript were performed on Chinese patients. Chinese studies show that psoriasis vulgaris accounts for 82. The intake of polyunsaturated acids was inversely associated with biomarkers of inflammation (C-reactive protein CRP, interleukin IL -6, and TNF- ), while intake of trans and saturated acids was positively associated with levels of CRP and IL-6. Osteoarthritis (OA) is a type of joint disease that results from breakdown of joint cartilage and underlying bone. Diagnosis is typically based on signs and symptoms, with medical imaging and other tests occasionally used to either support or rule out other problems. If pain interferes with normal life despite other treatments, joint replacement surgery may help. A study of mice found natural female hormones to be protective while injections of the male hormone dihydrotestosterone reduced protection.

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