Keywords: biologics, nail psoriasis, topical therapy, systemic therapy. It is possible to observe an isolated involvement of a few fingers or lesions of all nails on both hands and feet. Evaluation of the efficacy of acitretin therapy for nail psoriasis. Nail psoriasis affects up to 78 per cent of patients with psoriasis, in some it is their only sign. This Italian study aimed to evaluate the therapeutic efficacy of acitretin in patients with isolated nail psoriasis. Clinical evaluation at six months showed that a quarter of patients show complete clearing of the nail psoriasis. Importantly, 70-80 of patients with psoriatic arthritis have nail psoriasis. In this overview, we review the clinical manifestations of psoriasis affecting the nails, the common differential diagnosis of nail psoriasis, Nail Psoriasis Severity Index and the various diagnostic aids for diagnosing nail psoriasis especially, the cases with isolated nail involvement. Evaluation of the efficacy of acitretin therapy for nail psoriasis.
Doses under 25mg/d may be indicated in combination therapy. Very few studies have evaluated the short-term efficacy of acitretin in plaque psoriasis. Numerous isolated cases in the literature demonstrate the efficacy of acitretin in the treatment of nail psoriasis. In an open study of 36 patients with moderate to severe nail psoriasis treated with acitretin at a dose of 0. Over half of patients with psoriasis have abnormal changes in their nails, which may appear before other skin symptoms. Some even withdraw from society and become isolated. Evaluation of the efficacy of acitretin therapy for nail psoriasis. Isolated nail involvement is seen in 5-10 of patients. Despite the advances in therapy for psoriasis vulgaris, the options for nail psoriasis are rather limited. Lack of clear evidence validating the efficacy of various treatments makes it difficult to select the optimal treatment. Calcipotriol twice daily application for 3-6 months has been evaluated in the treatment of nail psoriasis. Acitretin 10-50 mg/day is used as a single dose.
Medical and scientific articles about Psoriasis, written by A Tosti. To evaluate the therapeutic efficacy of acitretin in patients with isolated nail psoriasis. 6, Article, Ustekinumab for the treatment of nail psoriasis in heavily treated psoriatic patients. To evaluate the therapeutic efficacy of acitretin in patients with isolated nail psoriasis. Hair and nail adverse events during treatment with target therapies for metastatic melanoma. To evaluate the therapeutic efficacy of acitretin in patients with isolated nail psoriasis.
Guidelines For The Use Of Acitretin In Psoriasis
Objective: Efficacy of systemic retinoid therapy of nail psoriasis has never been assessed objectively. Evaluate therapeutic efficacy of acitretin in patients with isolated nail psoriasi.