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Condition(s): Moderate to Severe Chronic Plaque-Type Psoriasis

Psoriasis is associated with other serious health conditions, such as diabetes, heart disease and depression. This is the second-most common type of psoriasis, after plaque psoriasis. About 10 percent of people who get psoriasis develop guttate psoriasis. Scalp psoriasis can be very mild, with slight, fine scaling. The results of a static Physician’s Global Assessment (six-point scale assessing overall disease severity at the point of assessment as clear, nearly clear, mild, moderate, severe or very severe). Plaque psoriasis is a chronic autoimmune condition. It appears on the skin in patches of thick, red, scaly skin. Plaque psoriasis can be a very itchy and sometimes painful condition.

Efficacy of Atorvastatin as Adjunctive Treatment for Chronic Plaque Type Psoriasis 2Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin. There are five main types of psoriasis: plaque, guttate, inverse, pustular, and erythrodermic. 77 These medications are generally well-tolerated and limited long-term outcome data have demonstrated biologics to be safe for long-term use in moderate to severe plaque psoriasis. Watch this slideshow on psoriasis to see moderate to severe forms of this common skin condition. Learn about the different types (vulgaris, guttate, scalp, pustular, nails, etc.) as well as treatments. Psoriasis is an autoimmune disorder where rapid skin cell reproduction results in raised, red, dry, and scaly patches of skin. WebMD’s guide to psoriasis, including types, symptoms, and causes. Unpredictable and irritating, psoriasis is one of the most baffling and persistent of skin disorders. Some common symptoms for plaque psoriasis — the most common variety of the condition — include:. In severe cases, the plaques of irritated skin will grow and merge into one another, covering large areas.

Learn more about moderate to severe plaque psoriasis and find answers to common questions at Enbrel. Plaque psoriasis is a lifelong condition that causes dry, thick, scaly, red skin. ENBREL is indicated for the treatment of adult patients with chronic moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy. In a medical study of patients with JIA, side effects were generally similar in frequency and type as those seen in adult patients. Psoriasis is a common and chronic skin disorder but treatable skin disorder that affects 1 -2 of people in the U. See pictures, and read about psoriasis symptoms, treatment, diet tips, types, prognosis, and causes. HIV infection may prolong the severity and extent of the condition. Plaque psoriasis (see the image below) is rarely life threatening, but it often is intractable to treatment. Psoriasis, which manifests most often as plaque psoriasis, is a chronic, relapsing, inflammatory skin disorder with a strong genetic basis. Alteration of the balance of T-cell types. In a randomized study, adding a topical corticosteroid to etanercept therapy in patients with moderate to severe plaque psoriasis proved to be a more effective treatment than etanercept alone.

Psoriasis

Efficacy of Atorvastatin as Adjunctive Treatment for Chronic Plaque Type Psoriasis 3Psoriasis is a common; typically chronic papulosquamous skin disease that may be associated with a seronegative spondyloarthropathy. The type and clinical manifestations of psoriasis in a patient depend on a combination of genetic influences, environmental factors (i. Etanercept is given at a starting dose of 50 mg injected subcutaneously (SQ) twice weekly for 12 weeks followed by 50 mg once weekly for maintenance of moderate to severe chronic plaque psoriasis. Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma. Moderate and severe plaque psoriasis: cost-of-illness study in Italy. The most common form of the disease is chronic plaque psoriasis, affecting about 90 of psoriasis patients, with about 20 30. Measuring quality of life of patients with different clinical types of psoriasis using the SF-36. Most types of psoriasis go through cycles, flaring for a few weeks or months, then subsiding for a time or even going into complete remission. The most common form, plaque psoriasis causes dry, raised, red skin lesions (plaques) covered with silvery scales. Symptoms range from mild to severe, and psoriatic arthritis can affect any joint. Leads to joint problems, such as pain, swelling or inability to perform daily tasks. Psoriasis is a chronic inflammatory skin condition characterised by clearly defined, red and scaly plaques (thickened skin). An individual’s genetic profile influences their type of psoriasis and its response to treatment. Itch is mostly mild but may be severe in some patients, leading to scratching and lichenification (thickened leathery skin with increased skin markings). which is used to treat mild-to-moderate plaque psoriasis. psorinfo.com. Chronic plaque psoriasis is the most common type of psoriasis. www2.cochrane.org. The skin condition, psoriasis, may actually precede or follow psoriatic arthritis.

What Is Plaque Psoriasis?

Treatment options for moderate to severe psoriasis include topical and systemic medications, phototherapy, and excimer laser, Combination therapies are often more effective than one treatment alone. Psoriasis is a chronic skin disorder in which there are sharply defined red patches on the skin, covered by a silvery, flaky surface. The most common type is called plaque psoriasis, also known as psoriasis vulgaris. Psoriasis is a common chronic skin disorder typically characterized by erythematous papules and plaques with a silver scale, although other presentations occur. In practice, the efficacy/potency of a topical corticosteroid is dependent on many factors including skin type, plaque thickness, and, perhaps most importantly, compliance. Please click Search to find Psoriasis clinical trials and medical research studies. Patients Twenty-five patients with chronic plaque-type psoriasis. 5- 7 Based on these differences, broadband UV-B phototherapy is primarily indicated in patients with mild to moderate psoriasis, whereas for severe forms of PUVA is indicated. Psoralen UV-A on the other hand, remains the mainstay for patients with severe psoriasis whose conditions do not respond or cannot be controlled adequately by narrowband UV-B.

The most common type is called plaque psoriasis, also known as psoriasis vulgaris.