Parmi les traitements pour lutter contre le psoriasis, on retrouve les traitements oraux, par voix g n rale ou encore appel e traitements syst miques. Psoriasis is a common chronic skin disorder typically characterized by erythematous papules and plaques with a silver scale, although other presentations occur. Severe disease Severe psoriasis requires phototherapy or systemic therapies such as retinoids, methotrexate, cyclosporine, apremilast, or biologic immune modifying agents. Compared with treatment with non-biologic agents, biologic therapy did not appear to be a significant predictor of death, major adverse cardiovascular events (MACE), or malignancy. Treatment options for moderate to severe psoriasis include topical and systemic medications, phototherapy, and excimer laser. Cyclosporine therapy for children with psoriasis has not been well studied. JM, et al, Guidelines of care for the management of psoriasis and psoriatic arthritis.
The treatment paradigm for moderate-to-severe psoriasis has evolved into a non-stepwise approach in which, essentially, all patients should initially be considered for one of three approaches (phototherapy traditional systemic agents, or biologies). Papp KA, Langley RG, Sigurgeirsson B, et al. J.K., Brown, M.D., Headington, J.T. et al, Cyclosporine improves psoriasis in a double-blind study. M.J. et al, Treatment of psoriasis with intermittent short course cyclosporine (Neoral). 151Phillips, M.A., Graves, J.E., Nunley, J.R. Alopecia areata presenting in 2 kidney-pancreas transplant recipients taking cyclosporine. Dans les cas graves, l’atteinte cutane peut tre gnralise (rythrodermie) et il peut exister des atteintes des articulations.
Updates On Psoriasis And Cutaneous Oncology