Psoriasis is a common chronic skin disorder typically characterized by erythematous papules and plaques with a silver scale, although other presentations occur. Calcipotriene Calcipotriene (calcipotriol) is an established therapy in psoriasis. Many new uses for existing topical therapies have been developed, and there’s new data to support new combination therapies. Calcipotriene Ointment: A New Topical Treatment for Psoriasis.
Includes Calcipotriol side effects, interactions and indications. Psoriasis (treatment)Calcipotriene cream and ointment are indicated for the treatment of mild to moderate plaque psoriasis. Safety and efficacy have not been established. The safety and effectiveness of topical calcipotriene in dermatoses other than psoriasis have not been established. This study investigates a new indication for an FDA-approved topical medication, calcipotriol, for treatment of actinic keratosis, including how well it works and how safe it is when used in combination with the standard of care medication (5-fluorouracil) for the skin condition. Calcipotriene Ointment official prescribing information for healthcare professionals. Calcipotriene Ointment, 0.005, is indicated for the treatment of plaque psoriasis in adults. The safety and effectiveness of topical calcipotriene in dermatoses other than psoriasis have not been established.
Treatment of psoriasis vulgaris in adults. Safety and efficacy not established. Calcipotriol and Betamethasone Dipropionate for the Treatment of Psoriasis: A 52-Week Study. 3,4 Most adverse reactions relate to initial application, irritation to or aggravation of existing psoriatic lesions. Long-term effectiveness and safety of topical calcipotriene for psoriasis. Mean rate ratios for cleared psoriasis between treatment groups by investigator overall assessment. Longer trials are needed to establish whether use of topical calcipotriene improves the risk-benefit ratio by reducing the long-term risks of toxic effects.
Calcipotriol Drug Information, Professional
Topical treatment with vitamin D analogs and corticosteroids is the mainstay of first-line therapy for patients with localized psoriasis. 28,29Treatment of psoriatic plaques with the vitamin D analog calcipotriene suppresses the expression of alarmins, antimicrobial peptides that amplify inflammation. 13,44The clinical relevance of these findings has not yet been established. The Applicator may represent a more acceptable treatment delivery system for some patients with psoriasis vulgaris and may, therefore, promote long-term treatment adherence. Calcipotriene Calcipotriol Gel Psoriasis vulgaris Topical treatments Topical suspension. Superior efficacy of calcipotriene and betamethasone dipropionate aerosol foam versus ointment in patients with psoriasis vulgaris A randomized phase II study. Current guidelines for first-line treatment of psoriasis vulgaris recommend topical use of vitamin D analogues and corticosteroids, either as separate products used in combination or as fixed combination treatment (1010. A study of the safety and efficacy of calcipotriol and betamethasone dipropionate scalp formulation in the long-term management of scalp psoriasis.