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Association of psoriasis-like eruption and Kawasaki disease

Psoriasiform eruptions during Kawasaki disease (KD): A distinct phenotype. A psoriasis-like eruption develops in a subset of patients with Kawasaki disease (KD). Portions of this work were presented at the Society for Pediatric Dermatology Annual Meeting in Coeur d’Alene, ID, July 10-12, 2014. Association between psoriasis-like skin lesions during the acute or subacute phase of Kawasaki disease and greater coronary artery dilatation. Kawasaki disease patients who developed psoriasiform eruptions had significantly more dilated coronary arteries than did those who did not, as reflected in their median maximal echocardiographic z-score of 2. Psoriasis is a chronic, inflammatory papulosquamous disease with an estimated prevalence of 1 in children. 6 Psoriasis arising during the acute and convalescent phases of Kawasaki disease has been reported in infants as young as 3 months. Psoriatic arthritis is the most common comorbid association in childhood psoriasis but is infrequent in infants.

Association of psoriasis-like eruption and Kawasaki disease 2The subacute phase begins when fever, rash, and lymphadenopathy resolve at about one to two weeks after the onset of fever, but irritability, anorexia, and conjunctival injection persist. Gastrointestinal complications in Kawasaki disease are similar to those observed in Henoch-Sch nlein purpura, 69 such as: intestinal obstruction, 76 colon swelling, 77 intestinal ischemia, 78 intestinal pseudo-obstruction, 79 and acute abdomen. This association with tropospheric winds has been shown to be modulated at seasonal and interannual timescales by the El Ni o Southern Oscillation phenomenon, 105 further indicating the agent responsible for the disease is a wind-borne pathogen. Scarlet fever appears similar to Kawasaki’s disease in some aspects, but lacks the eye signs or the swollen, red fingers and toes. Ankylosing spondylitis is an autoimmune disease and is a type of arthritis of the spine. There is a strong familial association which has been demonstrated. If you notice symptoms, they might include: fever, flu-like symptoms, a rash, or a swollen eyelid. Dermatological (skin) manifestations may occur and include psoriasis, acne, and pustules on the palms of the hands and soles of the feet.

A psoriasis-like eruption develops in a subset of patients with Kawasaki disease (KD). Kawasaki disease (KD, previously called mucocutaneous lymph node syndrome) is one of the most common vasculitides of childhood. The characteristic bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, rash, extremity changes, and cervical lymphadenopathy typically develop after a brief nonspecific prodrome of respiratory or gastrointestinal symptoms 3-8 (see ‘Other findings’ below). Psoriasis in a 3-month-old infant with Kawasaki disease. Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) ISSN: 0378-6323 EISSN: 0973-3922 Vol. Although in many instances like pustular psoriasis, the predominantly epidermal neutrophilic infiltrates satisfy the technical criteria for a ND this review is focused on dermal neutrophilic infiltrates. Absence of such infiltrate in epidermolysis bullosa acquisita differentiates from DH, linear IgA dermatosis and DH-like drug eruption.

Kawasaki Disease

Kawasaki disease is an acute multisystem inflammatory disease of blood vessels (vasculitis) that most commonly affects infants and young children. Kids With Heart National Association for Children’s Heart Disorders, Inc.

Kawasaki Disease Research