Clinical features of PsA, including comorbid conditions and disease activity, contribute to reduced physical and psychosocial health-related quality of life. Psoriatic arthritis (PsA) is a chronic, progressive, inflammatory arthropathy associated with psoriasis. Because of the variety of cost-collection methods, patient populations, and differences among countries, it is difficult to compare costs in all studies; The objective of this study was to examine the risk of mortality in patients with PsA compared to matched controls and to patients with psoriasis. Patients with RA and psoriasis had elevated mortality compared to the general population. Psoriatic arthritis (PsA) is a chronic progressive inflammatory disease that affects over 500,000 Americans and can cause permanent joint damage and severe disability. Prevalence of comorbidities was highest among patients with RA in nearly all categories. Psoriatic arthritis is a major comorbidity of psoriasis that significantly impairs quality of life and physical function. First, a multicenter, cross-sectional, prospective cohort study of 1,511 adult psoriasis patients from Germany compared the clinical characteristics of patients with psoriatic arthritis versus those without psoriatic arthritis. The prevalence of sacroilitis in psoriatic arthritis: new perspectives from a large, multicenter cohort.
To determine whether the presence of psoriatic arthritis (PsA) is associated with greater comorbidity, in particular cardiovascular morbidity, compared to psoriasis without arthritis. The clinical database was used to identify the prevalence of cardiovascular and other comorbidities in both PsA and psoriasis without arthritis patients. Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. In a recent cross-sectional study by Husted et al., prevalence of cardiovascular morbidities was compared between 611 patients with PsA and 449 patients with psoriasis only 24. 3, including angina, myocardial infarction, cardiomyopathy, congestive heart failure, and cerebrovascular accident) among patients with PsA compared with those with psoriasis only. Psoriasis (PsC) is a chronic inflammatory skin disease with a prevalence of 1 3 in the general population 1. The exact prevalence of PsA among patients with PsC is unknown. The aim of our study was to compare QoL and function among patients with PsA and those with PsC, all of whom were clinically evaluated to ascertain disease extent and severity. Patients with PsA attending the Psoriatic Arthritis Clinic at the Toronto Western Hospital have been enrolled in a longitudinal observational cohort since 1978. New York: Springer, 2008:1707.
The purpose of this study was to compare the HRQL scores among patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS) and a selected sample of health people and determine their relationship with measures of clinical condition. The presence of comorbidity was ascertained through patient’s self-reports by the Self-Administered Comorbidity Questionnaire (SCQ). RA is the most frequent IRD, with a prevalence of 0.5 1. Our study indicates that disease burden in RA, PsA and ax-SpA may be more similar than previously demonstrated. The main objective of this study was to compare disease burden in rheumatoid arthritis (RA), psoriatic arthritis (PsA) and axial spondyloarthritis (ax-SpA). Psoriatic arthritis is an inflammatory arthritis affecting the joints and connective tissue and is associated with psoriasis of the skin or nails. Epidemiology. There is not a strong correlation between the severity of psoriasis and the development of arthritis although psoriatic arthritis may be present more frequently in patients with psoriasis attending dermatology clinics, compared to primary care. Men are more commonly affected by the spondylitic subtype, with higher incidence of the ‘rheumatoid’ pattern of disease among women.
Cardiovascular And Other Comorbidities In Patients With Psoriatic Arthritis: A Comparison With Patients With Psoriasis
Although psoriatic arthritis (PsA) is associated predominantly with skin and joint manifestations, it is now recognized that patients with PsA are often affected by numerous comorbidities (Figure) that carry significant morbidity and mortality. This article provides a general overview of key conclusions and endorsements of the new recommendations document. A recent Cleveland Clinic study2 demonstrated increased carotid intima-media thickness, a surrogate of atherosclerosis, and increased presence of carotid artery plaque in patients with PsA compared with psoriasis alone. Among patients with psoriasis, the increased prevalence of NAFLD is associated with psoriasis severity and concomitant PsA as well as other comorbidities common to PsA, such as metabolic syndrome, hypercholesterolemia, hypertriglyceridemia and obesity. Abstract: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an excess of cardiovascular disease (CVD) risk, estimated to be at least 50 greater when compared to the general population. Information on comorbidity, concomitant medication, and socioeconomic status was linked on an individual level. Patients with psoriatic arthritis may be more likely to receive treatment with glucocorticoids; hence, to attenuate the potential impact of glucocorticoids on the risk of DM, we excluded patients with psoriatic arthritis in a sensitivity analysis. In the current study, we compared the incidence rates of new-onset DM in patients with psoriasis with those of the general population in an unselected, nationwide register based cohort followed for a maximum of 13 years. Psoriatic arthritis is a chronic inflammatory arthritis that develops in at least 5 of patients with psoriasis. The association between psoriasis and arthritis was first made in the mid-19th century, but psoriatic arthritis was not clinically distinguished from rheumatoid arthritis (RA) until the 1960s. Juxta-articular new-bone formation (assigned a score of 1). Radiographic studies. A longitudinal cohort study was performed in a large United Kingdom medical record database,The Health Improvement Network (THIN), among patients with PsA, RA, or psoriasis with data from 1994-2010. Patients with RA and psoriasis had elevated mortality compared to the general population. Keywords: Mortality, Psoriatic Arthritis, Psoriasis, Rheumatoid Arthritis, Epidemiology. Prevalence of comorbidities was highest among patients with RA in nearly all categories.