Psoriasis is an autoimmune disease that causes raised, red, scaly patches to appear on the skin. Psoriasis is associated with other serious health conditions, such as diabetes, heart disease and depression. About 10 percent of people who get psoriasis develop guttate psoriasis. A collection of biological samples and clinical information used by qualified scientists to advance the field of psoriasis genetics. View the list of all psoriatic disease clinical trials and find one near you that works. The Immunological Basis for Treatment Resistance to Anti-TNF Treatments. Watch this slideshow on Psoriasis Symptoms, Causes and Treatment. Learn about this common itchy, red, scaly skin condition and how it may be treated with options such as topical ointments, phototherapy, natural remedies and more. Psoriasis can be associated with a destructive arthritis called psoriatic arthritis. See additional information: Disclaimer.
Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin. Psoriasis is associated with an increased risk of psoriatic arthritis, lymphomas, cardiovascular disease, Crohn’s disease, and depression. Genetic studies are valuable due to their ability to identify molecular mechanisms and pathways for further study and potential drug targets. If the clinical diagnosis is uncertain, a skin biopsy or scraping may be performed to rule out other disorders and to confirm the diagnosis. Psoriasis is a complex, chronic, multifactorial, inflammatory disease that involves hyperproliferation of the keratinocytes in the epidermis, with an increase in the epidermal cell turnover rate (see the image below). The diagnosis of psoriasis is clinical, and the type of psoriasis present affects the physical examination findings. View Table List. Read more about Psoriasis on Medscape. Related Reference Topics. Joint disease is associated with psoriasis in a significant proportion of patients (reported in one study to be 13. Add notes to any clinical page and create a reflective diary. Click to find out more.
Psoriasis: Symptoms, Pictures, Causes, And Treatments
View pictures, images, and photos of medical conditions and diseases such as skin problems. Browse Categories by List Form:. Learn how to identify various allergic skin conditions such as eczema, psoriasis, contact dermatitis, and more. Clinical Depression. Psoriasis is a chronic skin disorder that causes areas of thickened, inflamed, red skin, often covered with silvery scales. People who have depression often benefit from working with a psychologist, clinical social worker, or other therapist to discuss their illness and identify possible ways to cope. Some of the most relevant are listed below. See pictures, and read about other symptoms, causes, and treatment. See images, and learn about causes, medications, symptoms, and treatment. There is now no question that psoriasis is an inherited systemic inflammatory disease of immune dysfunction whose most obvious clinical feature is plaque of elevated, inflamed skin. Must Read Articles Related to Plaque Psoriasis. Sometimes linked to nail psoriasis. Discover the causes, symptoms and learn how to manage the condition. Psoriasis causes patches of thick red skin and silvery scales. This means you cannot get psoriasis from contact (e.g., touching skin patches) with someone who has it. Efforts to address psoriasis and psoriatic arthritis have typically focused on studying and treating individual patients and on clinical and biomedical research.
A related condition called psoriatic arthritis affects between 10 and 20 percent of those with psoriasis. We see a large number of people with psoriasis ranging from a few, minor spots to large, disfiguring patches. These studies allow us to offer the latest treatments and clinical trials to our patients before they are available elsewhere. In addition to the itching and pain psoriasis causes, the plaques can be embarrassing and limit your activities. Psoriasis is a common chronic, recurrent, immune mediated disease of the skin and joints. Patients with psoriasis have a reduction in their quality of life similar to or worse than patients with other chronic diseases, such as ischaemic heart disease and diabetes. Table 1 lists these and a few elements of each. Find patient medical information for Methotrexate (Anti-Rheumatic) oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Find patient medical information for Methotrexate (Anti-Rheumatic) oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis that has not responded to other treatments. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. Psoriasis is a common scaly skin condition resulting in red scaly and thickened patches of skin. Clinical features of flexural psoriasis. Flexural psoriasis responds quite well to topical treatment but often recurs. Combinations of the treatments listed above may be used, together with emollients. Related information. See the DermNet NZ bookstore.
Psoriasis causes skin cells to mature in less than a week. This disease is characterized by smooth, inflamed lesions and can be debilitating. Because the course of this disease varies with each individual, doctors must experiment with or combine different treatments to find the most effective therapy for a particular patient. This water-based gel has chemical properties similar to vitamin A. Psoriasis can be associated with arthritis, inflammatory bowel disease and depression. Penn’s world renowned Dermatologists provide expert treatment for Psoriasis. Browse our list of physicians. Find a Clinical Trial Learn about Translational Research. Appropriate medically acceptable imaging includes, but is not limited to, angiography, x-ray imaging, computerized axial tomography (CAT scan) or magnetic resonance imaging (MRI), with or without contrast material, myelography, and radionuclear bone scans. Polymyositis and dermatomyositis are related disorders that are characterized by an inflammatory process in striated muscle, occurring alone or in association with other autoimmune disorders or malignancy. Undifferentiated connective tissue disease is diagnosed when clinical features and serologic (blood test) findings, such as rheumatoid factor or antinuclear antibody (consistent with an autoimmune disorder) are present but do not satisfy the criteria for a specific disease. Extra-articular impairments may also meet listings in other body systems. Contact Dermatitis and Related Conditions Online Medical Reference – from diagnosis through treatment options. The potential for these substances to cause contact dermatitis varies greatly, and the severity of the dermatitis or eczema, the most common clinical expression, ranges from a mild, short-lived condition to a severe, persistent, job-threatening disease. Major causes of ACD are listed in Box 4. Environmental measures include eliminating hazardous materials or finding substitutes for them, isolating and enclosing the work process, providing exhaust ventilation, and observing good housekeeping.