Results: In all, 25 incident cases of psoriasis in patients receiving anti-TNF therapy and none in the comparison cohort were reported between January 2001 and July 2007. Patients were categorised as responders or non-responders based on their 6-month DAS28 scores according to the European League Against Rheumatism (EULAR) definition. A global phase III randomized controlled trial of etanercept in psoriasis: safety, efficacy, and effect of dose reduction. Individual patient data from Phase III etanercept trials is used to populate the model supported by published evidence from extensive literature searches. Psoriatic arthritis (PsA) is an inflammatory joint disease classified as one of the spondyloarthropathies, with severe impact on patient’s disability. A second dataset, from a cohort of patients based at the Academic Unit of Musculoskeletal Disease, University of Leeds, was used to examine health state utility and long-term progression in patients with PsA. We have assumed that the two prior DMARDs would be methotrexate and sulphasalazine and therefore, the most relevant comparator would be either combination therapy of methotrexate and ciclosporin or leflunomide. Patients with psoriasis are often affected by comorbidities, which largely influence treatment decisions. Characteristics of the study cohort. Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial.
Patient UK Rheumatoid arthritis MeSH D001172. edit on Wikidata. Rheumatoid arthritis (RA) is a long-lasting autoimmune disorder that primarily affects joints. The term rheumatoid arthritis is based on the Greek for watery and inflamed joints. Constitutional symptoms Constitutional symptoms including fatigue, low grade fever, malaise, morning stiffness, loss of appetite and loss of weight are common systemic manifestations seen in people with active RA. There are now 3 reported cases of PML with over 100,000 patients exposed. Medical and scientific articles about Psoriasis, published from Los Angeles area. 53, Article, Risk of myocardial infarction in psoriasis patients: a retrospective cohort study. 2015.