A Case of Psoriasis Vulgaris Complicated with an HIV Infection. Although the skin disease psoriasis was first recognized as a distinct disease as early as 1808 (1), its pathogenic mechanisms have eluded investigators for decades. HLA-B and HLA-C genes in familial psoriasis vulgaris (PV): evidence for genetic heterogeneity. Patients’ history was dominated by the psoriasis vulgaris. The objective of this study is to describe the epidemiological, clinical, and histological aspects of psoriasis complicated forms in patients admitted to the Dermatology Unit of Treichville University Hospital. Patients were screened for HIV infection in 43 cases (76.8).
Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin. About 75 of cases can be managed with creams alone. Psoriasis vulgaris (also known as chronic stationary psoriasis or plaque-like psoriasis) is the most common form and affects 85 90 of people with psoriasis. A much higher rate of psoriatic arthritis occurs in HIV-positive individuals with psoriasis than in those without the infection. It can occur at any age but the majority of cases first present before the age of 35 years. HIV infection and AIDS – although other comorbid skin conditions may mimic psoriasis. Second-line therapy which includes phototherapy, broad-band or narrow-band ultraviolet B light, with or without supervised application of complex topical therapies such as dithranol in Lassar’s paste or crude coal tar and photochemotherapy, psoralens in combination with UVA irradiation (PUVA), and non-biological systemic agents such as ciclosporin, methotrexate and acitretin. Psoriasis is a complex, chronic, multifactorial, inflammatory disease that involves hyperproliferation of the keratinocytes in the epidermis, with an increase in the epidermal cell turnover rate (see the image below). Pain (especially in erythrodermic psoriasis and in some cases of traumatized plaques or in the joints affected by psoriatic arthritis). Chronic stationary psoriasis (psoriasis vulgaris): Most common type of psoriasis; involves the scalp, extensor surfaces, genitals, umbilicus, and lumbosacral and retroauricular regions. HIV testing.
Herein, we report the case of an otherwise healthy, nonpromiscuous 29-year-old man who presented to our institution with an eight-week history of plaques with oyster shell-like scales on the trunk, extremities and genital area. In contrast, psoriasis vulgaris in patients with HIV may have scales that appear thick and oyster shell-like (i. Sequential development of psoriasis, alopecia universalis, and vitiligo vulgaris in a human immunodeficiency virus seropositive patient: A unique case report. A 60-year-old male patient was diagnosed HIV positive in April 2010, while screening as a preoperative work up for hernia surgery. Patient was diagnosed as psoriasis vulgaris in July 2010. These arthocutaneous diseases tend to occur in temporal proximity to the development of AIDS and AIDS related complex, and their clinical manifestations are unusually severe. Plaque psoriasis (psoriasis vulgaris), the most common form of the disease, is characterized by small, red bumps that enlarge, become inflamed, and form scales. The condition may be complicated by ARTHRITIS.
Any musculoskeletal syndrome in non-HIV infected patients can occur in HIV-infected patients; such syndromes may not be related to the HIV infection. Aureus and Streptococcus pneumoniae, commonly found in non-HIV infected patients with septic arthritis and bursitis, are causative factors in most reported cases of septic arthritis and bursitis in HIV-infected persons. (HLA) alleles found in patients with idiopathic (non-HIV) psoriasis vulgaris or psoriatic arthritis (such as Cw6, B13, or B17) occur with greater frequency among HIV-infected patients with psoriatic-like arthritis. One report(1) described nine patients with Reiter’s syndrome and AIDS-related complex, and subsequent reports described additional patients. Infection. Infections caused by viruses or bacteria can trigger some cases of psoriasis. Human immunodeficiency virus (HIV) is also associated with psoriasis. Secondary bacterial and fungal infections should be treated with antiseptics, antibiotics, or antifungals, depending on the pathogens. C consensus, disease-oriented evidence, usual practice, expert opinion, or case series. Toe web intertrigo complicated byCandida albicans infection. Seborrheic dermatitis and psoriasis vulgaris inversa may have presentations similar to intertrigo. Psoriasis is an immune-mediated, genetic disease manifesting in the skin or joints or both. Understanding the role of immune function in psoriasis and the interplay between the innate and adaptive immune system has helped to manage this complex disease, which affects patients far beyond the skin. These bacteria rarely cause infection in humans other than those with HIV or AIDS. Though psoriasis is a common skin disease, its definition by Ferdinand von Hebra as a distinct entity dates back only to the year 1841, and estimates of its prevalence around 2 percent, according to standard textbooks stem from only a few population-based studies. On the basis of association studies of three tightly linked susceptibility alleles (HLA-Cw6,14 HCR WWCC, 15 and the HLA-associated S gene16), PSORS1 appears to be associated with up to 50 percent of cases of psoriasis. In addition to small pustules that may occur in lesions of psoriasis vulgaris, various forms of pustular psoriasis have been described (Figure 1F). However, because of clinical similarities, psoriasis in patients with HIV infection may be misinterpreted as seborrheic eczema.
Ostraceous And Inverse Psoriasis With Psoriatic Arthritis As The Presenting Features Of Advanced Hiv Infection
The clinical type of psoriasis and severity of the disease should be established early to guide treatment. Psoriasis vulgaris or chronic plaque psoriasis is the most common clinical disease type.