We present a case successfully treated with low-dose intralesional MTX with no observed side effects in a 26-year-old female psoriatic patient suffering from nail dystrophy. Eur Acad Dermatol Venereol 2009; 23: 891. 895. Treatment of nail psoriasis includes different types of medications, from topical therapy to systemic therapy, according to the severity and extension of the disease. Severe 20-nail psoriasis successfully treated by low dose methotrexate. Dermatol Online J. 2009;15(11):812. Psoriasis is a common; typically chronic papulosquamous skin disease that may be associated with a seronegative spondyloarthropathy. A 2009 consensus conference advocates following the American College of Rheumatology guidelines for patients with no risk factors for liver injury and recommend considering liver biopsy or switching to another treatment after 3. Severe 20-nail psoriasis successfully treated by low dose methotrexate.
Most cases are not severe enough to affect general health and are treated in the outpatie. The management of nail psoriasis is reviewed in detail separately. Until 2009, calcipotriene was the only topical vitamin D analog available in the United States. Methotrexate is usually administered in an intermittent low-dose regimen such as once weekly. Treatment options for moderate to severe psoriasis include topical and systemic medications, phototherapy, and excimer laser, Combination therapies are often more effective than one treatment alone. About 20 of such cases evolve from psoriasis itself. Many patients are able to tolerate methotrexate with few side effects. It is also effective in a low-dose formulation for symptoms of nail psoriasis. 2009;10(5):319-324. Generally, topical treatment is sufficient to control psoriasis, while systemic treatment is reserved for moderate to severe psoriasis. Severe 20-nail psoriasis successfully treated by low dose methotrexate.Dermatol Online J,2009,15(11):8.
A study conducted in 2009 revealed that the psychosocial morbidity of psoriasis and impairment of quality of life is the same or worse than arthritis, diabetes or cancer. The incidence of psoriasis is much lower in dark-skinned West Africans and African-Americans than in light-skinned people of European ancestry. One may see pustular psoriasis of the nail unit, known as acrodermatitis continua, which starts as pustules under the nail and can result in extensive destruction of the nail plate.20. Yu J, Lee Y. Severe nail psoriasis successfully treated by low dose methotrexate. November 15, 2009. Psoriasis in a 3-month-old infant with Kawasaki disease. Severe 20-nail psoriasis successfully treated by low dose methotrexate. 219 Severe 20-nail psoriasis successfully treated by low dose methotrexate.
Treatment Of Psoriasis
For the treatment of moderate to severe plaque psoriasis of the scalp, the fixed-combination suspension containing betamethasone 0. These include phototherapy and systemic medications like methotrexate, retinoids, cyclosporine and biologics. Low dose cyclosporine, tetracycline and Grenz Ray therapy may be useful in treating PPP. NAPSI ranges from 0 to 8 for one nail and from 0 to 160 for all 20 nails. Hsu, C., Hsu, M.M., Lee, J.Y.; J Am Acad Dermatol. 2009 Mar. Severe 20-nail psoriasis successfully treated by low dose methotrexate. Lee, J.Y.; Dermatol Online J. Acitretin Biologics Methotrexate Psoriasis Psoriatic nail disease Severe scalp psoriasis TNF- inhibitor. The 24 selected topics from the 2009 Psoriasis Consensus Conference. O. Successful treatment of psoriatic nails with low-dose cyclosporine administration.