Skip to content

1,25-Dihydroxycholecalciferol and Cyclosporine Suppress Induction and Promote Resolution of Psoriasis in Human Skin Grafts Transplanted on to SCID Mice

1alpha,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. Dam TN(1), Kang S, Nickoloff BJ, Voorhees JJ. Author information: (1)Department of Dermatology, University of Michigan, Ann Arbor, USA. TNDamdadlnet.dk. 25-Dihydroxycholecalciferol and Cyclosporine Suppress Induction and Promote Resolution of Psoriasis in Human Skin Grafts Transplanted on to SCID Mice. 1′ 0 (. ) ( )) ‘ ), )-. ) 2 ‘ ‘ ‘ (&. 34 0 ‘ 0 5’ ) 4 ‘ &04 &0 0 &0)6 &0)4 ‘ ‘ ‘ ( )-.

1,25-Dihydroxycholecalciferol and Cyclosporine Suppress Induction and Promote Resolution of Psoriasis in Human Skin Grafts Transplanted on to SCID Mice 2(la,25-dihydroxycholecalciferol), the 1 a-hydroxylated. The huPBL-SCID mouse as a means to examine human immune function in vivo. Development of a human adaptive immune system in cord blood cell-transplanted mice. 1Abrams, J., Kelley, S., Hayes, E. et al, Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells. B.J. et al, 1a, 25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. Et al, T-lymphocyte dependence of psoriatic pathology in human psoriatic skin grafted to SCID mice. Transplantation.

Specifically, Bz-423 was found to suppress hyperplastic changes induced by all-trans retinoic acid (RA) in the epidermis of human skin in organ culture without affecting the structure of the dermis (Varani et al. Animals with the human skin transplants were divided into treatment groups (vehicle plus test reagent, vehicle alone, or clobetasol propionate). (1999) 1, 25-Dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. 1,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. In clones of human keratinocytes carrying from a single to numerous insertions of the vitamin D3 sensor, a sensitive sensor read-out is detected upon exposure to even low concentrations of vitamin D3 analogues. Figure 1. A genetic sensor system for detection of vitamin D analogues. Dam TN, Kang S, Nickoloff BJ, Voorhees JJ: 1alpha,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice.

Ebscohost

1Alpha,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. PubMed journal article Treatment of psoriasis with interleukin-1 was found in Unbound MEDLINE. Download PubMed App to iPhone, iPad, Android smartphone and tablet. The treatment of psoriasis with IL-10: rationale and review of the first clinical trials. 1alpha,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. Psoriasis xenograft transplantation models where human skin is transplanted onto immune-deficient mice are generally accepted in psoriasis research. Translating clinical activity and gene expression signatures of etanercept and ciclosporin to the psoriasis xenograft SCID mouse model. 1alpha,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. SCID mice reconstituted with human serum that contains anti-allergen IgE antibodies have positive immediate-type skin test responses to intradermal injec- tion of allergen 28. (1999) 1alpha,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. The Vitamin D3 Pathway in Human Skin and its Role for Regulation of Biological Processes. 1,25-Dihydroxyvitamin D3 production by human keratinocytes. J. Clin. 1alpha, 25-Dihydroxycholecalciferol and cyclosporin suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. 1alpha,25- dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice.

(bz-423), A Benzodiazepine, Suppresses Keratinocyte Proliferation And Has Antipsoriatic Activity In The Human Skin-severe, Combined Imm